Quick Answer
Hop Extract Sleep Randomized Trial has evidence relevant to strength of evidence and what the studies can or cannot prove, but conclusions should stay close to the cited sources. One representative finding is: Menopause is a critical stage of women's life associated with various complaints and distresses.
Key Takeaways
- 01Menopause is a critical stage of women's life associated with various complaints and distresses. [Abdi F (2016)]
- 02Vasomotor symptoms (VMS), such as hot flushes, night sweats, sleep disturbances, and fatigue, are the most common menopause symptoms affecting about 50% to 80% of middle-aged women. [Abdi F (2016)]
- 03The results correlated with the metabolism data and showed that hop extract and 6-PN preferentially enhanced P450 1A1 mRNA expression and increased P450 1A1/1B1 activity. [Wang S (2016)]
- 046-PN was found to be an AhR agonist that significantly induced XRE activation and inhibited 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced XRE activity. [Wang S (2016)]
The current Migaku evidence database contains 2 reusable source documents for Hop Extract Sleep Randomized Trial. This answer focuses on strength of evidence and what the studies can or cannot prove.
- Menopause is a critical stage of women's life associated with various complaints and distresses. [Abdi F (2016); evidence level 4]
- Vasomotor symptoms (VMS), such as hot flushes, night sweats, sleep disturbances, and fatigue, are the most common menopause symptoms affecting about 50% to 80% of middle-aged women. [Abdi F (2016); evidence level 4]
- The results correlated with the metabolism data and showed that hop extract and 6-PN preferentially enhanced P450 1A1 mRNA expression and increased P450 1A1/1B1 activity. [Wang S (2016); evidence level 4]
- 6-PN was found to be an AhR agonist that significantly induced XRE activation and inhibited 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced XRE activity. [Wang S (2016); evidence level 4]
- (hops) is a popular botanical dietary supplement used by women as a sleep aid and for postmenopausal symptom relief. [Wang S (2016); evidence level 4]
Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording.
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Sources