topicHops Sleep Quality Randomized Trial
claimWe also found a significant prolongation of the total duration in bed during the night (= 0.023,= 0.37) with an estimated increase in the duration in bed of 0.406 h (24.4 min) in the verum group compared to the placebo group (Table ).
evidence level2
citationSchicktanz Nathalie (2025)
sourceEffects of a Valerian‐Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: A Randomized Controlled Feasibility Trial
topicHops Sleep Quality Randomized Trial
claimThe exploratory analysis indicated that the valerian and hop‐fixed herbal combination (Ze 91019) significantly increased sleep duration compared to placebo, with an average increase of 21.7 min per night during the treatment period as measured by the Fitbit tracker.
evidence level2
citationSchicktanz Nathalie (2025)
sourceEffects of a Valerian‐Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: A Randomized Controlled Feasibility Trial
topicHops Sleep Quality Randomized Trial
claimMoreover, Ze 91019 significantly increased the sleep duration of the shortest night in the treatment period by 48.7 minutes.
evidence level2
citationSchicktanz Nathalie (2025)
sourceEffects of a Valerian‐Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: A Randomized Controlled Feasibility Trial
topicHops Sleep Quality Randomized Trial
claim2006 2006 2004 2007 2002 Valeriana officinalis Humulus lupulus Sleep disturbances affect a significant portion of the adult general population, with about 30% reporting insomnia symptoms (Morin et al.).
evidence level2
citationSchicktanz Nathalie (2025)
sourceEffects of a Valerian‐Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: A Randomized Controlled Feasibility Trial
topicHops Sleep Quality Randomized Trial
claimThis literature review summarizes the current evidence on the efficacy, safety, and mechanisms of action of commonly used supplements for sleep, including valerian, hops, kava, German chamomile, cherry, tryptophan, theanine, melatonin, magnesium, and zinc.
evidence level4
citationYeom JW (2024)
sourceHerbal and Natural Supplements for Improving Sleep: A Literature Review.
topicHops Sleep Quality Randomized Trial
claimHowever, the strength of the evidence varies with unestablished optimal dosages, formulations, and treatment durations.
evidence level4
citationYeom JW (2024)
sourceHerbal and Natural Supplements for Improving Sleep: A Literature Review.
topicHops Sleep Quality Randomized Trial
claimAlthough generally considered safe, these supplements are not without risks, such as rare but serious adverse effects associated with kava and potential interactions with prescription medications.
evidence level4
citationYeom JW (2024)
sourceHerbal and Natural Supplements for Improving Sleep: A Literature Review.
topicHops Sleep Quality Randomized Trial
claimObjective Herbal and natural supplements have gained popularity as alternative treatments to insomnia and sleep disorders due to their perceived safety and potential effectiveness.
evidence level4
citationYeom JW (2024)
sourceHerbal and Natural Supplements for Improving Sleep: A Literature Review.