topicHop Extract Sleep Randomized Trial
claimMenopause is a critical stage of women's life associated with various complaints and distresses.
evidence level4
citationAbdi F (2016)
sourceHops for Menopausal Vasomotor Symptoms: Mechanisms of Action.
Structured evidence table for Hop Extract Sleep Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Hop Extract Sleep Randomized Trial | Menopause is a critical stage of women's life associated with various complaints and distresses. | 4 | Abdi F (2016) | Hops for Menopausal Vasomotor Symptoms: Mechanisms of Action. |
| Hop Extract Sleep Randomized Trial | Vasomotor symptoms (VMS), such as hot flushes, night sweats, sleep disturbances, and fatigue, are the most common menopause symptoms affecting about 50% to 80% of middle-aged women. | 4 | Abdi F (2016) | Hops for Menopausal Vasomotor Symptoms: Mechanisms of Action. |
| Hop Extract Sleep Randomized Trial | The results correlated with the metabolism data and showed that hop extract and 6-PN preferentially enhanced P450 1A1 mRNA expression and increased P450 1A1/1B1 activity. | 4 | Wang S (2016) | Hop (Humulus lupulus L.) Extract and 6-Prenylnaringenin Induce P450 1A1 Catalyzed Estrogen 2-Hydroxylation. |
| Hop Extract Sleep Randomized Trial | 6-PN was found to be an AhR agonist that significantly induced XRE activation and inhibited 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced XRE activity. | 4 | Wang S (2016) | Hop (Humulus lupulus L.) Extract and 6-Prenylnaringenin Induce P450 1A1 Catalyzed Estrogen 2-Hydroxylation. |
| Hop Extract Sleep Randomized Trial | (hops) is a popular botanical dietary supplement used by women as a sleep aid and for postmenopausal symptom relief. | 4 | Wang S (2016) | Hop (Humulus lupulus L.) Extract and 6-Prenylnaringenin Induce P450 1A1 Catalyzed Estrogen 2-Hydroxylation. |
| Hop Extract Sleep Randomized Trial | In addition to its efficacy for menopausal symptoms, hops can also modulate the chemical estrogen carcinogenesis pathway and potentially protect women from breast cancer. | 4 | Wang S (2016) | Hop (Humulus lupulus L.) Extract and 6-Prenylnaringenin Induce P450 1A1 Catalyzed Estrogen 2-Hydroxylation. |
Source documents