Is Electrolyte Supplementation Endurance Randomized Trial safe?

The current Migaku evidence database contains 2 reusable source documents for Electrolyte Supplementation Endurance Randomized Trial. This answer focuses on safety, limits, and clinician-discussion contexts. - Results Calcium was associated with lower heart rates 45 min after starting the infusion (P = .002). [Fielding CL (2023); evidence level 2] - An increase in plasma phosphorus concentration (P = .03) was associated with calcium administration. [Fielding CL (2023); evidence level 2] - Background The addition of calcium to resuscitation fluids is a common practice in horses, but studies evaluating the effects of calcium supplementation are limited. [Fielding CL (2023); evidence level 2] - In healthy horses, decreases in heart rate and changes in serum electrolyte concentrations have been reported. [Fielding CL (2023); evidence level 2] - Recent evidence also suggests improvements in cognitive performance during exercise, including focus and reaction time, especially with exogenous ketone esters []. [Siri Morvarid (2025); evidence level 3] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.