Structured evidence table for Biotin Supplementation Nail Health Randomized Trial, generated from 1 reusable source document in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Biotin Supplementation Nail Health Randomized Trial | However, deficiency may occur in specific at-risk groups, including individuals receiving long-term antibiotic therapy (which disrupts intestinal flora), chronic anticonvulsant therapy (which alters biotin metabolism), or total parenteral nutrition without adequate supplementation. | 4 | Cervantes A (2025) | Biotin Deficiency |
| Biotin Supplementation Nail Health Randomized Trial | While biotin supplements are widely marketed for hair, skin, and nail health, limited clinical evidence supports their use in individuals without a documented deficiency. | 4 | Cervantes A (2025) | Biotin Deficiency |
| Biotin Supplementation Nail Health Randomized Trial | Moreover, high-dose biotin supplementation has been shown to interfere with immunoassays, particularly those measuring thyroid hormones and cardiac biomarkers (eg, troponins), which may result in false-positive or false-negative results and lead to inappropriate diagnostic or therapeutic decisions. | 4 | Cervantes A (2025) | Biotin Deficiency |
| Biotin Supplementation Nail Health Randomized Trial | Biotin (vitamin B7) is a water-soluble B-complex vitamin that plays a vital role in cellular metabolism. | 4 | Cervantes A (2025) | Biotin Deficiency |
Source documents