Does Creatine Sleep Quality Meta-Analysis work?

Updated June 2026

Quick Answer

Creatine Sleep Quality Meta-Analysis has evidence relevant to strength of evidence and what the studies can or cannot prove, but conclusions should stay close to the cited sources. One representative finding is: Clinically, EIMD is commonly reflected by delayed-onset muscle soreness (DOMS), elevated circulating creatine kinase (CK), and reduced neuromuscular performance [].

Key Takeaways

  • 01Clinically, EIMD is commonly reflected by delayed-onset muscle soreness (DOMS), elevated circulating creatine kinase (CK), and reduced neuromuscular performance []. [Hou Chunlin (2026)]
  • 02Massage and cryotherapy have been associated with reductions in DOMS and fatigue [], and massage has also shown favourable effects on short-term recovery of performance []. [Hou Chunlin (2026)]
  • 03As a result, interventions that are beneficial immediately after exercise may not retain their effects during delayed recovery. [Hou Chunlin (2026)]
  • 041 2 1 3 High-intensity training and competitive sport can induce exercise-induced muscle damage (EIMD), characterised by mechanical disruption of sarcomeres, impaired excitation-contraction coupling, and a subsequent inflammatory response [,]. [Hou Chunlin (2026)]
The current Migaku evidence database contains 2 reusable source documents for Creatine Sleep Quality Meta-Analysis. This answer focuses on strength of evidence and what the studies can or cannot prove. - Clinically, EIMD is commonly reflected by delayed-onset muscle soreness (DOMS), elevated circulating creatine kinase (CK), and reduced neuromuscular performance []. [Hou Chunlin (2026); evidence level 1] - Massage and cryotherapy have been associated with reductions in DOMS and fatigue [], and massage has also shown favourable effects on short-term recovery of performance []. [Hou Chunlin (2026); evidence level 1] - As a result, interventions that are beneficial immediately after exercise may not retain their effects during delayed recovery. [Hou Chunlin (2026); evidence level 1] - 1 2 1 3 High-intensity training and competitive sport can induce exercise-induced muscle damage (EIMD), characterised by mechanical disruption of sarcomeres, impaired excitation-contraction coupling, and a subsequent inflammatory response [,]. [Hou Chunlin (2026); evidence level 1] - Melatonin significantly reduced creatine kinase levels (SMD = 0.59, 95% CI: 0.29 to 0.89, p I 2 = 0%), with non-significant effects on lactate dehydrogenase (SMD = 0.45, 95% CI: -0.03 to 0.94, p = 0.07, I 2 = 56%). [Guo J (2026); evidence level 1] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Acute and Delayed Effects of Post-Exercise Recovery Strategies on Explosive Performance and Markers of Muscle Damage: A Systematic Review and Network Meta-Analysis
  2. Timing-dependent effects of melatonin supplementation on exercise performance and exercise-induced muscle damage: a systematic review and meta-analysis.