What does the evidence say about Citrulline Resistance Exercise Performance Meta-Analysis?

The current Migaku evidence database contains 2 reusable source documents for Citrulline Resistance Exercise Performance Meta-Analysis. This answer focuses on benefits, uncertainty, and practical interpretation. - Based on these mechanisms, CM ingestion is potentially well suited to resistance exercise performance on the premise that these mechanisms would lead to increased training output, and this could increase the potential strength and/or power improvements from training. [Gough Lewis A. (2026); evidence level 2] - These collection of studies have reported improvements in the number of repetitions performed to failure, a reduced rate of perceived exertion and/or delayed-onset muscle soreness. [Gough Lewis A. (2026); evidence level 2] - For example, Pérez -Guisado and Jakeman (2010) [] reported total reps during four sets to failure (at 80% 1RM) were improved significantly following ingestion of 8 g CM. [Gough Lewis A. (2026); evidence level 2] - 1 2 3 4 Citrulline malate (CM) is an inorganic salt synthesised from the non-essential amino acid L-citrulline and the tricarboxylic cycle intermediate malate. [Gough Lewis A. (2026); evidence level 2] - 1 2 3 4 2 5 6 L-citrulline is a non-essential amino acid that is found primarily in watermelons, cucumbers, and other melons []. [Gonzalez Adam M. (2023); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.