Magnesium Cortisol Meta-analysis: What the Evidence Says

Quick Answer

Magnesium Cortisol Meta-analysis has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are systematic review, so conclusions should be framed as evidence-aware guidance rather than medical advice.

Key Takeaways

• This page is generated only from sources stored in the Migaku evidence knowledge base.
• Current evidence mix: 1 systematic review, 1 research article.
• Claims should be interpreted with the source type, study design, population, and publication date in mind.
• This article is educational and does not replace care from a qualified clinician.

Evidence Map

What The Sources Report

• Beyond daytime fatigue, cognitive impairment, and increased vulnerability to mood disorders, it has also been associated with endocrine and metabolic disturbances, including altered cortisol secretion, dysregulated glucose and lipid metabolism, and perturbations in sex hormone profiles. [Hu Yun (2026); evidence level 1]
• Acupuncture is commonly employed to address numerous clinical issues, especially those associated with pathological alterations in neuroendocrine function, including menopause, depression, and insomnia. [Hu Yun (2026); evidence level 1]
• Studies investigating the relationship between OLP and sleep quality report that OLP patients seem to have worse sleep quality compared to the general population, where poor sleep has been claimed as a risk factor for the onset and aggravation of OLP. [Wegner Éverton Adriano (2026); evidence level 4]
• It was suggested that dysregulation in melatonin secretion would be associated with the pathogenesis of several autoimmune diseases, such as systemic lupus erythematosus, multiple sclerosis, and rheumatoid arthritis. [Wegner Éverton Adriano (2026); evidence level 4]

How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

Practical Interpretation

There is at least one systematic-review style source in the current set, so it deserves more weight than single-study evidence. For magnesium cortisol meta-analysis, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

References

• Hu Yun (2026). Sleep and endocrine effects of acupuncture for insomnia: a systematic review and meta-analysis of randomized controlled trials. DOI: 10.3389/fmed.2026.1807826. PMCID: PMC13095780. PMID: 42023088. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13095780/
• Wegner Éverton Adriano (2026). Association of Sleep Quality, Nutritional Factors, and Salivary Melatonin and Cortisol Levels with Oral Lichen Planus: A Case–Control Study. DOI: 10.3390/biomedicines14061275. PMCID: PMC13296431. PMID: 42351703. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13296431/

Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.