L-citrulline Exercise Performance Randomized Trial: What the Evidence Says

Quick Answer

L-citrulline Exercise Performance Randomized Trial has 2 source documents in the current Migaku evidence database. The strongest available sources in this first pass are randomized trial, so conclusions should be framed as evidence-aware guidance rather than medical advice.

Key Takeaways

• This page is generated only from sources stored in the Migaku evidence knowledge base.
• Current evidence mix: 1 randomized trial, 1 research article.
• Claims should be interpreted with the source type, study design, population, and publication date in mind.
• This article is educational and does not replace care from a qualified clinician.

Evidence Map

What The Sources Report

• Strategies that support repeated high-intensity sprint performance are of considerable interest in competitive sprinting and team sports; however, evidence regarding acute citrulline malate (CM) supplementation during recovery intervals remains limited. [Yamanaka R (2026); evidence level 2]
• This study examined the effects of acute CM supplementation on repeated 100 m sprint performance and rating of perceived exertion (RPE) in trained sprinters. [Yamanaka R (2026); evidence level 2]
• Through its involvement in NO-related pathways, L-ARG supplementation has been associated with changes in vascular function and blood flow, which may influence exercise-related physiological responses (,-). [Uçar Halil (2026); evidence level 4]
• However, the findings across these studies remain inconsistent, and conclusive evidence supporting clear performance or recovery benefits has yet to be established. [Uçar Halil (2026); evidence level 4]

How To Read This Evidence

Evidence level 1 generally reflects systematic reviews or meta-analyses. Level 2 includes randomized trials, guidelines, or public-health guidance. Level 3 usually reflects observational or narrative-review evidence. Level 4 is weaker or early-stage evidence. The level is a sorting aid, not a final quality grade.

Practical Interpretation

There is trial evidence in the current set, but population and intervention details still matter. For l-citrulline exercise performance randomized trial, the next editorial step is to add more targeted sources and separate strong findings from early or indirect evidence.

Limits Of This First Pass

This is a small-batch MVP article. It uses the first ingested sources for this topic and should be expanded with more targeted searches, license review, and human editorial checks before being treated as a definitive review.

References

• Yamanaka R (2026). Effects of Acute Citrulline Malate Supplementation on Repeated 100 m Sprint Performance in Trained Sprinters: A Randomized Crossover Study.. DOI: 10.3390/sports14040143. PMCID: PMC13120297. PMID: 42043075. https://pmc.ncbi.nlm.nih.gov/articles/PMC13120297/
• Uçar Halil (2026). Acute effects of citrulline malate and L-arginine, alone and in combination, on anaerobic performance indicators in highly trained taekwondo athletes. DOI: 10.3389/fnut.2026.1788549. PMCID: PMC13057471. PMID: 41958907. License: CC BY 4.0. https://pmc.ncbi.nlm.nih.gov/articles/PMC13057471/

Safety Note

Health information can change, and individual risk depends on medical history, medications, pregnancy status, age, and diagnosis. Talk with a qualified clinician before changing treatment, supplement, or medication routines.