Structured evidence table for Zinc Supplementation Acne Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Zinc Supplementation Acne Meta-Analysis | During pregnancy, zinc supplementation is frequently recommended to enhance maternal immunity, reduce the risk of infections, and support overall gestational health (). | 3 | Mugundan Uma Maheshwari (2026) | Could excessive zinc supplementation during pregnancy cause menkes disease? A hypothesis worth investigating |
| Zinc Supplementation Acne Meta-Analysis | However, direct clinical evidence remains limited, with only a small number of studies in pregnant women demonstrating an inverse relationship between zinc supplementation and copper status and no large-scale epidemiological data linking this interaction to neonatal outcomes. | 3 | Mugundan Uma Maheshwari (2026) | Could excessive zinc supplementation during pregnancy cause menkes disease? A hypothesis worth investigating |
| Zinc Supplementation Acne Meta-Analysis | As a result, excessive zinc consumption can indirectly cause copper deficiency even if copper intake remains adequate, which is depicted in. | 3 | Mugundan Uma Maheshwari (2026) | Could excessive zinc supplementation during pregnancy cause menkes disease? A hypothesis worth investigating |
| Zinc Supplementation Acne Meta-Analysis | 1 2 Menkes disease (MD) is a rare X-linked recessive neurodegenerative disorder caused by mutations in the ATP7A gene, which encodes a critical copper-transporting ATPase involved in cellular copper efflux and distribution. | 3 | Mugundan Uma Maheshwari (2026) | Could excessive zinc supplementation during pregnancy cause menkes disease? A hypothesis worth investigating |
| Zinc Supplementation Acne Meta-Analysis | These treatments show varying degrees of efficacy and improved safety profiles, but most lack head-to-head comparisons with isotretinoin. | 4 | Tommasino N (2026) | Beyond Isotretinoin: A Narrative Review of Emerging Systemic Therapies for Moderate-to-Severe Acne. |
| Zinc Supplementation Acne Meta-Analysis | Conclusion Several systemic options beyond isotretinoin have emerged, showing potential in specific subgroups or as adjunctive therapies. | 4 | Tommasino N (2026) | Beyond Isotretinoin: A Narrative Review of Emerging Systemic Therapies for Moderate-to-Severe Acne. |
| Zinc Supplementation Acne Meta-Analysis | However, further large-scale comparative studies are needed to define their roles within evidence-based acne management algorithms. | 4 | Tommasino N (2026) | Beyond Isotretinoin: A Narrative Review of Emerging Systemic Therapies for Moderate-to-Severe Acne. |
| Zinc Supplementation Acne Meta-Analysis | Background Acne vulgaris is a common inflammatory skin disorder with significant psychosocial impact. | 4 | Tommasino N (2026) | Beyond Isotretinoin: A Narrative Review of Emerging Systemic Therapies for Moderate-to-Severe Acne. |
Source documents