topicTurmeric Joint Pain Randomized Trial
claimBackground This umbrella review synthesizes evidence from systematic reviews and meta-analyses evaluating the efficacy and safety of diverse curcumin formulations in the treatment of osteoarthritis (OA).
evidence level1
citationShi C (2026)
sourceEfficacy and safety of different curcumin formulations in osteoarthritis: an umbrella review of systematic reviews.
topicTurmeric Joint Pain Randomized Trial
claimConclusion Curcumin-based interventions show promise for OA symptom management, with efficacy signals comparable to NSAIDs and appear to have a more favorable tolerability profile in the available studies, while addressing bioavailability challenges.
evidence level1
citationShi C (2026)
sourceEfficacy and safety of different curcumin formulations in osteoarthritis: an umbrella review of systematic reviews.
topicTurmeric Joint Pain Randomized Trial
claimThe objective is to assess curcumin's therapeutic potential and inform future formulation development.
evidence level1
citationShi C (2026)
sourceEfficacy and safety of different curcumin formulations in osteoarthritis: an umbrella review of systematic reviews.
topicTurmeric Joint Pain Randomized Trial
claimNational dietary guidelines from several countries (eg, the United States, United Kingdom, and Australia) recommend the consumption of spices to lower sodium intake.The National Institutes of Health (NIH)–funded Dietary Approaches to Stop Hypertension (DASH) healthy eating plan replaces salt with spices and herbs as a means to lower blood pressure without medication.
evidence level3
citationDiacova Tatiana (2026)
sourceSpices Beyond Antioxidants: From the Gut to the Brain
topicTurmeric Joint Pain Randomized Trial
claimIt was also demonstrated that salt intake was associated with regional metabolic activity in the insula and orbitofrontal cortex (OFC) areas of the brain.The administration of capsaicin (chili pepper) in the Li et al.
evidence level3
citationDiacova Tatiana (2026)
sourceSpices Beyond Antioxidants: From the Gut to the Brain
topicTurmeric Joint Pain Randomized Trial
claim(2013) To investigate whether spice (poly)phenols reduce GI and systemic formation of cytotoxic lipid peroxidation products and increase NO formation, thereby leading to improved endothelial vascular function n  = 11 men with type 2 diabetes RCT 2 test meals, 1 wk apart  Zhang et al.
evidence level3
citationDiacova Tatiana (2026)
sourceSpices Beyond Antioxidants: From the Gut to the Brain
topicTurmeric Joint Pain Randomized Trial
claimHerbs and spices have been used in various countries around the world for centuries.
evidence level3
citationDiacova Tatiana (2026)
sourceSpices Beyond Antioxidants: From the Gut to the Brain