Structured evidence table for Selenium Thyroid Hormone Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Selenium Thyroid Hormone Meta-Analysis | Subclinical hypothyroidism has been associated with metabolic disturbances, increased cardiovascular risk, and reduced quality of life, highlighting the need for effective management strategies [,]. | 1 | Stanchev Pavel (2026) | Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto’s Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis |
| Selenium Thyroid Hormone Meta-Analysis | It is thought to enhance TSH signaling and support thyroid hormone synthesis, with emerging clinical evidence suggesting a beneficial effect on thyroid function parameters []. | 1 | Stanchev Pavel (2026) | Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto’s Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis |
| Selenium Thyroid Hormone Meta-Analysis | Despite these promising findings, the available evidence remains limited, and there is currently no consensus regarding the clinical benefit of combination therapy over selenium alone. | 1 | Stanchev Pavel (2026) | Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto’s Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis |
| Selenium Thyroid Hormone Meta-Analysis | 1 2 3 2 3 Hashimoto’s thyroiditis (HT) is the most common autoimmune thyroid disorder and the leading cause of hypothyroidism in iodine-sufficient regions worldwide []. | 1 | Stanchev Pavel (2026) | Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto’s Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis |
| Selenium Thyroid Hormone Meta-Analysis | It is associated with elevated anti-thyroid peroxidase antibodies (TPOAb) and often anti-thyroglobulin antibodies (TgAb) (). | 4 | Personius Lydia (2026) | Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis |
| Selenium Thyroid Hormone Meta-Analysis | The incidence of HT has increased over recent decades and is higher with advancing age, in women, and in iodine-sufficient populations (,). | 4 | Personius Lydia (2026) | Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis |
| Selenium Thyroid Hormone Meta-Analysis | Wet cupping was associated with a statistically significant reduction in anti-thyroid autoantibody levels and a decrease in TSH despite stable thyroid hormone dosing (). | 4 | Personius Lydia (2026) | Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis |
| Selenium Thyroid Hormone Meta-Analysis | 1 2 3 4 Hashimoto’s thyroiditis (HT) is an autoimmune disorder that has been well documented as the leading cause of hypothyroidism and the most common form of thyroiditis (). | 4 | Personius Lydia (2026) | Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis |
Source documents