evidence table

Saffron Sleep Onset Meta-Analysis Evidence Table

Structured evidence table for Saffron Sleep Onset Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Saffron Sleep Onset Meta-AnalysisDifficulties in accessing healthcare, their high costs, personal preferences, and the perceived safety of medicinal herbs have contributed to the increased usage of herbalism [,,].1Hasheminasab Fatemeh Sadat (2026)Adverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
Saffron Sleep Onset Meta-AnalysisGiven their popularity, it is crucial to have up‐to‐date risk and benefit assessments on these herbal products [].1Hasheminasab Fatemeh Sadat (2026)Adverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
Saffron Sleep Onset Meta-AnalysisTherefore, compiling a systematic review of human studies with the aim of summarizing the available evidence on the side effects ofnot only fills the gap in the literature but also seems essential for physicians, researchers, and health policymakers to use this widely used medicinal plant safely and rationally.1Hasheminasab Fatemeh Sadat (2026)Adverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
Saffron Sleep Onset Meta-Analysissativus 1 1 2 2 3 Saffron (L.) is a sophisticated spice with culinary and therapeutic importance [].1Hasheminasab Fatemeh Sadat (2026)Adverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
Saffron Sleep Onset Meta-AnalysisLevodopa remains the most effective therapy; however, it is associated with a wide range of side effects and shows little to no efficacy against non-motor symptoms.4Galla R (2026)Neuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.
Saffron Sleep Onset Meta-AnalysisThe results demonstrated that the combined treatment (Mix) significantly restored cell viability after 6-OHDA exposure and more effectively reduced oxidative and nitrosative stress, as well as lipid peroxidation, compared to single compounds.4Galla R (2026)Neuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.
Saffron Sleep Onset Meta-AnalysisIn conclusion, these results indicate that the Mix has a suggest a synergistic-like impact on various disease-causing pathways in PD, highlighting its promise as a multi-faceted neuroprotective approach.4Galla R (2026)Neuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.
Saffron Sleep Onset Meta-AnalysisParkinson's disease (PD) is a neurodegenerative disorder characterised by dopamine deficiency and the accumulation of α-synuclein (α-syn), which aggregates into pathological inclusions known as Lewy bodies and Lewy neurites, distributed across multiple brain regions, with a particular prevalence in dopaminergic neurons.4Galla R (2026)Neuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.
topicSaffron Sleep Onset Meta-Analysis
claimDifficulties in accessing healthcare, their high costs, personal preferences, and the perceived safety of medicinal herbs have contributed to the increased usage of herbalism [,,].
evidence level1
citationHasheminasab Fatemeh Sadat (2026)
sourceAdverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
topicSaffron Sleep Onset Meta-Analysis
claimGiven their popularity, it is crucial to have up‐to‐date risk and benefit assessments on these herbal products [].
evidence level1
citationHasheminasab Fatemeh Sadat (2026)
sourceAdverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
topicSaffron Sleep Onset Meta-Analysis
claimTherefore, compiling a systematic review of human studies with the aim of summarizing the available evidence on the side effects ofnot only fills the gap in the literature but also seems essential for physicians, researchers, and health policymakers to use this widely used medicinal plant safely and rationally.
evidence level1
citationHasheminasab Fatemeh Sadat (2026)
sourceAdverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
topicSaffron Sleep Onset Meta-Analysis
claimsativus 1 1 2 2 3 Saffron (L.) is a sophisticated spice with culinary and therapeutic importance [].
evidence level1
citationHasheminasab Fatemeh Sadat (2026)
sourceAdverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
topicSaffron Sleep Onset Meta-Analysis
claimLevodopa remains the most effective therapy; however, it is associated with a wide range of side effects and shows little to no efficacy against non-motor symptoms.
evidence level4
citationGalla R (2026)
sourceNeuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.
topicSaffron Sleep Onset Meta-Analysis
claimThe results demonstrated that the combined treatment (Mix) significantly restored cell viability after 6-OHDA exposure and more effectively reduced oxidative and nitrosative stress, as well as lipid peroxidation, compared to single compounds.
evidence level4
citationGalla R (2026)
sourceNeuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.
topicSaffron Sleep Onset Meta-Analysis
claimIn conclusion, these results indicate that the Mix has a suggest a synergistic-like impact on various disease-causing pathways in PD, highlighting its promise as a multi-faceted neuroprotective approach.
evidence level4
citationGalla R (2026)
sourceNeuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.
topicSaffron Sleep Onset Meta-Analysis
claimParkinson's disease (PD) is a neurodegenerative disorder characterised by dopamine deficiency and the accumulation of α-synuclein (α-syn), which aggregates into pathological inclusions known as Lewy bodies and Lewy neurites, distributed across multiple brain regions, with a particular prevalence in dopaminergic neurons.
evidence level4
citationGalla R (2026)
sourceNeuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.

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Source documents

  1. Adverse Events of Saffron ( Crocus sativus L.): Systematic Review of Current Evidence
  2. Neuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.