Saffron Sleep Meta-Analysis Evidence Table

Structured evidence table for Saffron Sleep Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Saffron Sleep Meta-AnalysisHowever, due to some potentially significant adverse events associated with its medicinal use at higher doses or prolonged administration, clinical monitoring should be considered.1Hasheminasab FS (2026)Adverse Events of Saffron (<i>Crocus sativus</i> L.): Systematic Review of Current Evidence.
Saffron Sleep Meta-AnalysisBackground Crocus sativus L., commonly known as saffron, is a widely used spice with a rich history of culinary and medicinal applications.1Hasheminasab FS (2026)Adverse Events of Saffron (<i>Crocus sativus</i> L.): Systematic Review of Current Evidence.
Saffron Sleep Meta-AnalysisThis systematic review aims to compile human data from studies on monopreparations of C.1Hasheminasab FS (2026)Adverse Events of Saffron (<i>Crocus sativus</i> L.): Systematic Review of Current Evidence.
Saffron Sleep Meta-AnalysisLevodopa remains the most effective therapy; however, it is associated with a wide range of side effects and shows little to no efficacy against non-motor symptoms.4Galla R (2026)Neuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.
Saffron Sleep Meta-AnalysisThe results demonstrated that the combined treatment (Mix) significantly restored cell viability after 6-OHDA exposure and more effectively reduced oxidative and nitrosative stress, as well as lipid peroxidation, compared to single compounds.4Galla R (2026)Neuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.
Saffron Sleep Meta-AnalysisIn conclusion, these results indicate that the Mix has a suggest a synergistic-like impact on various disease-causing pathways in PD, highlighting its promise as a multi-faceted neuroprotective approach.4Galla R (2026)Neuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.
Saffron Sleep Meta-AnalysisParkinson's disease (PD) is a neurodegenerative disorder characterised by dopamine deficiency and the accumulation of α-synuclein (α-syn), which aggregates into pathological inclusions known as Lewy bodies and Lewy neurites, distributed across multiple brain regions, with a particular prevalence in dopaminergic neurons.4Galla R (2026)Neuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.

Source documents

  1. Adverse Events of Saffron (<i>Crocus sativus</i> L.): Systematic Review of Current Evidence.
  2. Neuroprotective Effects of the Combination of Green Tea, Saffron, Docosahexaenoic Acid, and α-Lipoic Acid in an In Vitro Model of Parkinson's Disease.