topicQuercetin Nasal Allergy Meta-Analysis
claimCytokine profiling showed that quercetin significantly suppressed the expression of IL-4 and TNF-α, and increased the expression of IFN-γ, which may contribute to the underlying anti-inflammatory mechanism of quercetin through Th1/Th2 immune rebalancing.
evidence level1
citationLv Z (2025)
sourceQuercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.
topicQuercetin Nasal Allergy Meta-Analysis
claimConclusion Quercetin exhibits strong anti-allergic effects in preclinical models through suppression of IgE, modulation of immune cells, regulation of cytokine network, and reduction of histamine.
evidence level1
citationLv Z (2025)
sourceQuercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.
topicQuercetin Nasal Allergy Meta-Analysis
claimBackground Quercetin is a naturally occurring flavonoid widely present in fruits, vegetables and tea with multiple pharmacological activities, including immunomodulatory, anti-allergic, antioxidant and anti-inflammatory properties.
evidence level1
citationLv Z (2025)
sourceQuercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.
topicQuercetin Nasal Allergy Meta-Analysis
claimPreclinical studies have indicated the potential to ameliorate allergic symptoms in animal models, but comprehensive synthesis is still scarce.
evidence level1
citationLv Z (2025)
sourceQuercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.
topicQuercetin Nasal Allergy Meta-Analysis
claimCurrent therapies mainly alleviate symptoms without addressing underlying immune dysfunction, which has increased interest in nutritional bioactive compounds as preventive or modulatory agents.
evidence level3
citationZafrilla P (2025)
sourceDietary Bioactive Compounds and Their Role in Allergy Prevention: A Comprehensive Review.
topicQuercetin Nasal Allergy Meta-Analysis
claimThis review summarizes evidence on omega-3 polyunsaturated fatty acids, vitamin D, curcumin, ginger bioactives, quercetin, and epigallocatechin gallate (EGCG) in allergy prevention and management.
evidence level3
citationZafrilla P (2025)
sourceDietary Bioactive Compounds and Their Role in Allergy Prevention: A Comprehensive Review.
topicQuercetin Nasal Allergy Meta-Analysis
claimGinger constituents ([6]-gingerol, [6]-shogaol) modulate Th1/Th2 balance, mast-cell activity, and oxidative stress, with early clinical evidence in rhinitis and asthma.
evidence level3
citationZafrilla P (2025)
sourceDietary Bioactive Compounds and Their Role in Allergy Prevention: A Comprehensive Review.
topicQuercetin Nasal Allergy Meta-Analysis
claimBackground/Objectives: Allergic diseases are highly prevalent worldwide and represent a significant public health burden.
evidence level3
citationZafrilla P (2025)
sourceDietary Bioactive Compounds and Their Role in Allergy Prevention: A Comprehensive Review.