evidence table
Quercetin Inflammation Meta-Analysis Evidence Table
Structured evidence table for Quercetin Inflammation Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Quercetin Inflammation Meta-Analysis | Although existing therapies, including corticosteroids, antivirals, and immunosuppressants, can delay progression of disease, they are often associated with high costs, side effects, and decreased long-term efficacy []. | 3 | Dogra Shivani (2026) | Redox Reprogramming of the Diseased Liver by Dietary Flavonoids: From Molecular Signalling to Gut–Liver Crosstalk |
| Quercetin Inflammation Meta-Analysis | Flavonoids comprise a structurally diverse group of naturally occurring polyphenolic compounds abundantly found in grains, tea, fruits, vegetables, and numerous medicinal plants [,,]. | 3 | Dogra Shivani (2026) | Redox Reprogramming of the Diseased Liver by Dietary Flavonoids: From Molecular Signalling to Gut–Liver Crosstalk |
| Quercetin Inflammation Meta-Analysis | The purpose of this review is to consolidate current mechanistic evidence of flavonoid-mediated redox regulation in liver disease, with particular emphasis on intracellular signalling pathways and gut–liver interactions, and to assess their potential therapeutic relevance. | 3 | Dogra Shivani (2026) | Redox Reprogramming of the Diseased Liver by Dietary Flavonoids: From Molecular Signalling to Gut–Liver Crosstalk |
| Quercetin Inflammation Meta-Analysis | It plays a central role in maintaining the metabolism of lipids, proteins, and carbohydrates, thereby supporting overall physiological balance. | 3 | Dogra Shivani (2026) | Redox Reprogramming of the Diseased Liver by Dietary Flavonoids: From Molecular Signalling to Gut–Liver Crosstalk |
| Quercetin Inflammation Meta-Analysis | Background Liver inflammation and fibrosis are directly associated with non-alcoholic fatty liver disease (NAFLD). | 4 | Alqahtani SA (2026) | Quercetin Attenuates Non-Alcoholic Fatty Liver Disease in Association with the Inhibition of Hepatic IL-1β/iNOS and IL-1β/CD45 Axes of Inflammation and Fibrosis Accompanied by Reduced Endogenous Metabolites and Apoptosis. |
| Quercetin Inflammation Meta-Analysis | NAFLD was also associated with the upregulation of hepatic IL-1β, iNOS, CD45, and apoptosis (p53). | 4 | Alqahtani SA (2026) | Quercetin Attenuates Non-Alcoholic Fatty Liver Disease in Association with the Inhibition of Hepatic IL-1β/iNOS and IL-1β/CD45 Axes of Inflammation and Fibrosis Accompanied by Reduced Endogenous Metabolites and Apoptosis. |
| Quercetin Inflammation Meta-Analysis | Biomarkers of fibrosis (TIMP-1 and α-SMA) were also elevated, and fibrosis was confirmed in the model group by increased collagen deposition and elevated stages of fibrosis score (Stage 1 to 2 of Brunt's NASH classification). | 4 | Alqahtani SA (2026) | Quercetin Attenuates Non-Alcoholic Fatty Liver Disease in Association with the Inhibition of Hepatic IL-1β/iNOS and IL-1β/CD45 Axes of Inflammation and Fibrosis Accompanied by Reduced Endogenous Metabolites and Apoptosis. |
| Quercetin Inflammation Meta-Analysis | Dysregulation of the potent pro-inflammatory cytokine interleukin-1 beta (IL-1β), inducible nitric oxide synthase (iNOS), and tissue leukocyte infiltration (CD45 +ve) are connected with multiorgan injury and fibrosis. | 4 | Alqahtani SA (2026) | Quercetin Attenuates Non-Alcoholic Fatty Liver Disease in Association with the Inhibition of Hepatic IL-1β/iNOS and IL-1β/CD45 Axes of Inflammation and Fibrosis Accompanied by Reduced Endogenous Metabolites and Apoptosis. |
Source documents
- Redox Reprogramming of the Diseased Liver by Dietary Flavonoids: From Molecular Signalling to Gut–Liver Crosstalk
- Quercetin Attenuates Non-Alcoholic Fatty Liver Disease in Association with the Inhibition of Hepatic IL-1β/iNOS and IL-1β/CD45 Axes of Inflammation and Fibrosis Accompanied by Reduced Endogenous Metabolites and Apoptosis.