evidence table

Quercetin Allergy Meta-Analysis Evidence Table

Name: Quercetin Allergy Meta-Analysis Evidence Table
Creator: Migaku
License: https://creativecommons.org/licenses/by/4.0/

Structured evidence table for Quercetin Allergy Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topic	claim	evidence level	citation	source
Quercetin Allergy Meta-Analysis	Although both the innate and adaptive immune systems have important roles in maintaining homeostasis with the environment (), allergies result from a similar interaction of genetic factors and environmental factors, at the phenotypic level, leading to immunological dysregulation at the molecular and cellular levels (;).	1	Lv Zeyi (2025)	Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies
Quercetin Allergy Meta-Analysis	Di Lorenzo et al., 2017 Lambrecht and Hammad, 2015 Akdis, 2012 Pawankar, 2014 Warren et al., 2021 Pathogenesis of allergic diseases is considered to involve types I-IV hypersensitivity mechanisms classified by Gell and Coombs, which are often associated with coexisting multiple reaction types.	1	Lv Zeyi (2025)	Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies
Quercetin Allergy Meta-Analysis	Histamines, proteases, and chemotactic factors released by the mast cells have been identified as the main mediators of increased vascular permeability and smooth muscle contraction in acute anaphylactic shock ().	1	Lv Zeyi (2025)	Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies
Quercetin Allergy Meta-Analysis	Allergic diseases (AD) are a heterogeneous group of hypersensitivity diseases caused by deviant immune responses against normally innocuous environmental antigens.	1	Lv Zeyi (2025)	Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies
Quercetin Allergy Meta-Analysis	Current therapies mainly alleviate symptoms without addressing underlying immune dysfunction, which has increased interest in nutritional bioactive compounds as preventive or modulatory agents.	3	Zafrilla P (2025)	Dietary Bioactive Compounds and Their Role in Allergy Prevention: A Comprehensive Review.
Quercetin Allergy Meta-Analysis	This review summarizes evidence on omega-3 polyunsaturated fatty acids, vitamin D, curcumin, ginger bioactives, quercetin, and epigallocatechin gallate (EGCG) in allergy prevention and management.	3	Zafrilla P (2025)	Dietary Bioactive Compounds and Their Role in Allergy Prevention: A Comprehensive Review.
Quercetin Allergy Meta-Analysis	Ginger constituents ([6]-gingerol, [6]-shogaol) modulate Th1/Th2 balance, mast-cell activity, and oxidative stress, with early clinical evidence in rhinitis and asthma.	3	Zafrilla P (2025)	Dietary Bioactive Compounds and Their Role in Allergy Prevention: A Comprehensive Review.
Quercetin Allergy Meta-Analysis	Background/Objectives: Allergic diseases are highly prevalent worldwide and represent a significant public health burden.	3	Zafrilla P (2025)	Dietary Bioactive Compounds and Their Role in Allergy Prevention: A Comprehensive Review.