evidence table
Quercetin Allergy Meta-Analysis Evidence Table
Structured evidence table for Quercetin Allergy Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Quercetin Allergy Meta-Analysis | Although both the innate and adaptive immune systems have important roles in maintaining homeostasis with the environment (), allergies result from a similar interaction of genetic factors and environmental factors, at the phenotypic level, leading to immunological dysregulation at the molecular and cellular levels (;). | 1 | Lv Zeyi (2025) | Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies |
| Quercetin Allergy Meta-Analysis | Di Lorenzo et al., 2017 Lambrecht and Hammad, 2015 Akdis, 2012 Pawankar, 2014 Warren et al., 2021 Pathogenesis of allergic diseases is considered to involve types I-IV hypersensitivity mechanisms classified by Gell and Coombs, which are often associated with coexisting multiple reaction types. | 1 | Lv Zeyi (2025) | Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies |
| Quercetin Allergy Meta-Analysis | Histamines, proteases, and chemotactic factors released by the mast cells have been identified as the main mediators of increased vascular permeability and smooth muscle contraction in acute anaphylactic shock (). | 1 | Lv Zeyi (2025) | Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies |
| Quercetin Allergy Meta-Analysis | Allergic diseases (AD) are a heterogeneous group of hypersensitivity diseases caused by deviant immune responses against normally innocuous environmental antigens. | 1 | Lv Zeyi (2025) | Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies |
| Quercetin Allergy Meta-Analysis | Current therapies mainly alleviate symptoms without addressing underlying immune dysfunction, which has increased interest in nutritional bioactive compounds as preventive or modulatory agents. | 3 | Zafrilla P (2025) | Dietary Bioactive Compounds and Their Role in Allergy Prevention: A Comprehensive Review. |
| Quercetin Allergy Meta-Analysis | This review summarizes evidence on omega-3 polyunsaturated fatty acids, vitamin D, curcumin, ginger bioactives, quercetin, and epigallocatechin gallate (EGCG) in allergy prevention and management. | 3 | Zafrilla P (2025) | Dietary Bioactive Compounds and Their Role in Allergy Prevention: A Comprehensive Review. |
| Quercetin Allergy Meta-Analysis | Ginger constituents ([6]-gingerol, [6]-shogaol) modulate Th1/Th2 balance, mast-cell activity, and oxidative stress, with early clinical evidence in rhinitis and asthma. | 3 | Zafrilla P (2025) | Dietary Bioactive Compounds and Their Role in Allergy Prevention: A Comprehensive Review. |
| Quercetin Allergy Meta-Analysis | Background/Objectives: Allergic diseases are highly prevalent worldwide and represent a significant public health burden. | 3 | Zafrilla P (2025) | Dietary Bioactive Compounds and Their Role in Allergy Prevention: A Comprehensive Review. |
Source documents