topicPhosphatidylserine Sleep Latency Meta-Analysis
claimOur results reveal that orexin/receptor systems are associated with numerous functions.
evidence level3
citationZhang Shengnan (2025)
sourceSignal transduction, dimerization, and therapeutic targeting of Orexin and receptor systems
topicPhosphatidylserine Sleep Latency Meta-Analysis
claimIn another study on chronic unpredictable mild stress (CUMS) depression model rats, OXA was found to significantly improve the pain threshold and reduce the pain perception ability of depressed rats ().
evidence level3
citationZhang Shengnan (2025)
sourceSignal transduction, dimerization, and therapeutic targeting of Orexin and receptor systems
topicPhosphatidylserine Sleep Latency Meta-Analysis
claimperipherally-derived peripherally administered Kastin and Akerstrom, 1999 Mondal et al., 1999 Current evidence regarding the BBB permeability of orexins remains inconclusive.
evidence level3
citationZhang Shengnan (2025)
sourceSignal transduction, dimerization, and therapeutic targeting of Orexin and receptor systems
topicPhosphatidylserine Sleep Latency Meta-Analysis
claimKukkonen et al., 2024 Alain et al., 2021 Smolinska et al., 2015 Orexin receptors (OXRs) belong to the class A (rhodopsin-like) G protein-coupled receptor (GPCR) family.
evidence level3
citationZhang Shengnan (2025)
sourceSignal transduction, dimerization, and therapeutic targeting of Orexin and receptor systems