topicMultivitamin Cognitive Performance Randomized Trial
claimThe d emographic shift toward an older population is accelerating the prevalence of age-related diseases.
evidence level2
citationKuerec AH (2026)
sourcePROMETHEUS clinical trial protocol: tailoring healthy ageing with lifestyle and nutraceuticals.
topicMultivitamin Cognitive Performance Randomized Trial
claimPrecision geromedicine represents a paradigm shift in targeting the biological processes of ageing to optimise health and healthspan, which likely requires multimodal tailored interventions.
evidence level2
citationKuerec AH (2026)
sourcePROMETHEUS clinical trial protocol: tailoring healthy ageing with lifestyle and nutraceuticals.
topicMultivitamin Cognitive Performance Randomized Trial
claimThe multivitamin with guaraná treatment was associated with significantly enhanced Serial Threes performance and self-rated contentment.
evidence level4
citationScholey A (2013)
sourceAcute effects of different multivitamin mineral preparations with and without Guaraná on mood, cognitive performance and functional brain activation.
topicMultivitamin Cognitive Performance Randomized Trial
claimfMRI revealed that both multivitamin treatments increased activation in areas associated with working memory and attentional processing, with the effect being greater in the multivitamin with guaraná condition.
evidence level4
citationScholey A (2013)
sourceAcute effects of different multivitamin mineral preparations with and without Guaraná on mood, cognitive performance and functional brain activation.
topicMultivitamin Cognitive Performance Randomized Trial
claimFurthermore, they demonstrate for the first time increased brain activation from multivitamin preparations both with and without guaraná, as measured using fMRI.
evidence level4
citationScholey A (2013)
sourceAcute effects of different multivitamin mineral preparations with and without Guaraná on mood, cognitive performance and functional brain activation.
topicMultivitamin Cognitive Performance Randomized Trial
claimPrevious work has identified the positive effects of the acute administration of a multivitamin-guaraná preparation during an effortful executive/working memory task.
evidence level4
citationScholey A (2013)
sourceAcute effects of different multivitamin mineral preparations with and without Guaraná on mood, cognitive performance and functional brain activation.