Msm Joint Stiffness Meta-Analysis Evidence Table

Structured evidence table for Msm Joint Stiffness Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Msm Joint Stiffness Meta-AnalysisAssessment of outcomes among these groups relied on the Western Ontario and McMaster University Osteoarthritis Index (WOMAC), with weighted mean differences (WMDs) and associated 95% confidence intervals (CIs) computed.1Du P (2025)Efficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysis.
Msm Joint Stiffness Meta-AnalysisConclusion In comparison to the placebo, NEM (for stiffness), Aflapin (for pain), and E-OA-07 (for knee function and WOMAC total score) were discerned as the most effective interventions for the treatment of KOA.1Du P (2025)Efficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysis.
Msm Joint Stiffness Meta-AnalysisBackground Knee osteoarthritis (KOA) stands as a prevalent clinical condition that frequently affects individuals.1Du P (2025)Efficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysis.
Msm Joint Stiffness Meta-AnalysisA growing body of research has highlighted the potential advantages of dietary supplements, including glucosamine and chondroitin, in the management of KOA.1Du P (2025)Efficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysis.
Msm Joint Stiffness Meta-AnalysisTo ensure a robust synthesis of evidence, we conducted a systematic search of PubMed, Embase, and Web of Science (2020-2025) for high-quality clinical trials, meta-analyses, and guidelines.4Wang H (2026)Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.
Msm Joint Stiffness Meta-AnalysisThis narrative review evaluates the clinical transition from reactive, surgery-centric models to a proactive, integrated framework to mitigate the profound socioeconomic burden and functional decline associated with the disease.4Wang H (2026)Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.
Msm Joint Stiffness Meta-AnalysisWe synthesized evidence across non-pharmacological rehabilitation, pharmacotherapy, and advanced joint-preserving surgeries, emphasizing optimal intervention windows and stage-specific mechanobiological requirements.4Wang H (2026)Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.
Msm Joint Stiffness Meta-AnalysisKnee osteoarthritis (KOA) is a primary driver of global disability, currently affecting over 365 million adults, with projections suggesting a 74.9% increase by 2050.4Wang H (2026)Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.
topicMsm Joint Stiffness Meta-Analysis
claimAssessment of outcomes among these groups relied on the Western Ontario and McMaster University Osteoarthritis Index (WOMAC), with weighted mean differences (WMDs) and associated 95% confidence intervals (CIs) computed.
evidence level1
citationDu P (2025)
sourceEfficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysis.
topicMsm Joint Stiffness Meta-Analysis
claimConclusion In comparison to the placebo, NEM (for stiffness), Aflapin (for pain), and E-OA-07 (for knee function and WOMAC total score) were discerned as the most effective interventions for the treatment of KOA.
evidence level1
citationDu P (2025)
sourceEfficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysis.
topicMsm Joint Stiffness Meta-Analysis
claimBackground Knee osteoarthritis (KOA) stands as a prevalent clinical condition that frequently affects individuals.
evidence level1
citationDu P (2025)
sourceEfficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysis.
topicMsm Joint Stiffness Meta-Analysis
claimA growing body of research has highlighted the potential advantages of dietary supplements, including glucosamine and chondroitin, in the management of KOA.
evidence level1
citationDu P (2025)
sourceEfficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysis.
topicMsm Joint Stiffness Meta-Analysis
claimTo ensure a robust synthesis of evidence, we conducted a systematic search of PubMed, Embase, and Web of Science (2020-2025) for high-quality clinical trials, meta-analyses, and guidelines.
evidence level4
citationWang H (2026)
sourceEvolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.
topicMsm Joint Stiffness Meta-Analysis
claimThis narrative review evaluates the clinical transition from reactive, surgery-centric models to a proactive, integrated framework to mitigate the profound socioeconomic burden and functional decline associated with the disease.
evidence level4
citationWang H (2026)
sourceEvolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.
topicMsm Joint Stiffness Meta-Analysis
claimWe synthesized evidence across non-pharmacological rehabilitation, pharmacotherapy, and advanced joint-preserving surgeries, emphasizing optimal intervention windows and stage-specific mechanobiological requirements.
evidence level4
citationWang H (2026)
sourceEvolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.
topicMsm Joint Stiffness Meta-Analysis
claimKnee osteoarthritis (KOA) is a primary driver of global disability, currently affecting over 365 million adults, with projections suggesting a 74.9% increase by 2050.
evidence level4
citationWang H (2026)
sourceEvolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.

Source documents

  1. Efficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysis.
  2. Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions.