Structured evidence table for Methylsulfonylmethane Joint Pain Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Methylsulfonylmethane Joint Pain Meta-Analysis | Effective management of KOA is therefore crucial not only for improving the patient’s quality of life but also for reducing the associated economic burden. | 1 | Sumsuzzman Dewan Md. (2024) | Comparative Efficacy of Glucosamine-Based Combination Therapies in Alleviating Knee Osteoarthritis Pain: A Systematic Review and Network Meta-Analysis |
| Methylsulfonylmethane Joint Pain Meta-Analysis | 5 6 7 8 9 10 11 12 13 13 Managing KOA pain mainly relies on NSAIDs, but their prolonged use raises the risk of gastrointestinal and cardiovascular adverse events []. | 1 | Sumsuzzman Dewan Md. (2024) | Comparative Efficacy of Glucosamine-Based Combination Therapies in Alleviating Knee Osteoarthritis Pain: A Systematic Review and Network Meta-Analysis |
| Methylsulfonylmethane Joint Pain Meta-Analysis | However, the American College of Rheumatology conditionally does not recommend the use of glucosamine for treating KOA []. | 1 | Sumsuzzman Dewan Md. (2024) | Comparative Efficacy of Glucosamine-Based Combination Therapies in Alleviating Knee Osteoarthritis Pain: A Systematic Review and Network Meta-Analysis |
| Methylsulfonylmethane Joint Pain Meta-Analysis | 1 2 3 4 Osteoarthritis (OA) remains a major global health issue, with its prevalence rising with age and varying across different geographic regions and anatomic sites []. | 1 | Sumsuzzman Dewan Md. (2024) | Comparative Efficacy of Glucosamine-Based Combination Therapies in Alleviating Knee Osteoarthritis Pain: A Systematic Review and Network Meta-Analysis |
| Methylsulfonylmethane Joint Pain Meta-Analysis | Temporomandibular disorders (TMDs) encompass a spectrum of musculoskeletal and joint conditions of the masticatory system that frequently lead to chronic pain, limited function, and reduced quality of life. | 3 | Gazali M (2026) | Diagnosis-based pathways for conservative and minimally invasive management of temporomandibular disorders: a scoping review. |
| Methylsulfonylmethane Joint Pain Meta-Analysis | Although conservative and minimally invasive approaches are recommended as first-line therapies, their comparative efficacy remains unclear.This scoping review mapped evidence from randomized controlled trials (RCTs) published between 2015 and 2025 to identify diagnosis-based effective management pathways for TMDs. | 3 | Gazali M (2026) | Diagnosis-based pathways for conservative and minimally invasive management of temporomandibular disorders: a scoping review. |
| Methylsulfonylmethane Joint Pain Meta-Analysis | Overall, the evidence from the past decade supports a diagnosis-driven, stepwise model that emphasizes conservative multimodal care as the cornerstone of TMD management. | 3 | Gazali M (2026) | Diagnosis-based pathways for conservative and minimally invasive management of temporomandibular disorders: a scoping review. |
Source documents