evidence table

Melatonin Sleep Latency Randomized Trial Evidence Table

Structured evidence table for Melatonin Sleep Latency Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Melatonin Sleep Latency Randomized TrialWhile exogenous melatonin supplements are used to manage the condition, there is limited evidence available on the efficacy of sustained-release (SR) melatonin formulations.2Thanawala S (2026)Efficacy and Safety of Sustained-Release Melatonin Capsules (2 mg) in Healthy Adults with Poor Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.
Melatonin Sleep Latency Randomized TrialSupplementation with melatonin-SR 2 mg capsule at night for 28 days was found to be effective and safe in improving objective and subjective sleep quality outcomes and overall well-being in the trial population.2Thanawala S (2026)Efficacy and Safety of Sustained-Release Melatonin Capsules (2 mg) in Healthy Adults with Poor Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.
Melatonin Sleep Latency Randomized TrialSleep disturbances and poor sleep quality are growing public health concerns, adversely affecting both physical and mental health.2Thanawala S (2026)Efficacy and Safety of Sustained-Release Melatonin Capsules (2 mg) in Healthy Adults with Poor Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.
Melatonin Sleep Latency Randomized TrialSleep is a complex biological process whose evolutionary purpose has remained equivocal for quite some time.More recently, however, compelling evidence has emerged, leading to recognition of the numerous metabolic and physiological functions sleep contributes to and actively supports.4Conti Federica (2026)Dietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
Melatonin Sleep Latency Randomized TrialEpidemiological studies have revealed that sleep deprivation is associated with an increased risk of all-cause mortality,alongside numerous chronic conditions imposing a heavy burden on our healthcare and socioeconomic systems alike,including cardiovascular disease, stroke, obesity, type 2 diabetes, and various types of cancer and neurological disorders.4Conti Federica (2026)Dietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
Melatonin Sleep Latency Randomized TrialThe scope of this narrative review is to summarize the available evidence on the mechanisms of action and potential benefits of the above-listed nutrients in the context of acute or chronic sleep disturbances.4Conti Federica (2026)Dietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
Melatonin Sleep Latency Randomized Trial, , Over the past few decades, there has been an increasing appreciation of the negative impact of sleep disturbances and circadian misalignments on all aspects of human health and performance, ranging from objective alertness, learning, memory, and cognition to emotional regulation, social wellbeing and, most remarkably, physical health.4Conti Federica (2026)Dietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicMelatonin Sleep Latency Randomized Trial
claimWhile exogenous melatonin supplements are used to manage the condition, there is limited evidence available on the efficacy of sustained-release (SR) melatonin formulations.
evidence level2
citationThanawala S (2026)
sourceEfficacy and Safety of Sustained-Release Melatonin Capsules (2 mg) in Healthy Adults with Poor Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.
topicMelatonin Sleep Latency Randomized Trial
claimSupplementation with melatonin-SR 2 mg capsule at night for 28 days was found to be effective and safe in improving objective and subjective sleep quality outcomes and overall well-being in the trial population.
evidence level2
citationThanawala S (2026)
sourceEfficacy and Safety of Sustained-Release Melatonin Capsules (2 mg) in Healthy Adults with Poor Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.
topicMelatonin Sleep Latency Randomized Trial
claimSleep disturbances and poor sleep quality are growing public health concerns, adversely affecting both physical and mental health.
evidence level2
citationThanawala S (2026)
sourceEfficacy and Safety of Sustained-Release Melatonin Capsules (2 mg) in Healthy Adults with Poor Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.
topicMelatonin Sleep Latency Randomized Trial
claimSleep is a complex biological process whose evolutionary purpose has remained equivocal for quite some time.More recently, however, compelling evidence has emerged, leading to recognition of the numerous metabolic and physiological functions sleep contributes to and actively supports.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicMelatonin Sleep Latency Randomized Trial
claimEpidemiological studies have revealed that sleep deprivation is associated with an increased risk of all-cause mortality,alongside numerous chronic conditions imposing a heavy burden on our healthcare and socioeconomic systems alike,including cardiovascular disease, stroke, obesity, type 2 diabetes, and various types of cancer and neurological disorders.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicMelatonin Sleep Latency Randomized Trial
claimThe scope of this narrative review is to summarize the available evidence on the mechanisms of action and potential benefits of the above-listed nutrients in the context of acute or chronic sleep disturbances.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicMelatonin Sleep Latency Randomized Trial
claim, , Over the past few decades, there has been an increasing appreciation of the negative impact of sleep disturbances and circadian misalignments on all aspects of human health and performance, ranging from objective alertness, learning, memory, and cognition to emotional regulation, social wellbeing and, most remarkably, physical health.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review

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Source documents

  1. Efficacy and Safety of Sustained-Release Melatonin Capsules (2 mg) in Healthy Adults with Poor Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.
  2. Dietary Protocols to Promote and Improve Restful Sleep: A Narrative Review