topicMarine Collagen Skin Meta-Analysis
claimIn HUVECs, GAE increased viability, migration, tube formation, and vascular endothelial growth factor (VEGF) expression.
evidence level4
citationJeong S (2026)
sourceProangiogenic and Collagen-Promoting Effects of a 70% Ethanol Extract of <i>Grateloupia angusta</i> in Cutaneous Wound Models.
topicMarine Collagen Skin Meta-Analysis
claimIn mice, GAE accelerated wound closure from day 3 to day 5 and increased granulation/matrix with higher proliferating cell nuclear antigen (PCNA) and cluster of differentiation 31 (CD31) expression after a single topical application.
evidence level4
citationJeong S (2026)
sourceProangiogenic and Collagen-Promoting Effects of a 70% Ethanol Extract of <i>Grateloupia angusta</i> in Cutaneous Wound Models.
topicMarine Collagen Skin Meta-Analysis
claimIn addition, keratin 14 (K14) expression was restored in GAE-treated wound tissues, suggesting improved epidermal re-epithelialization.
evidence level4
citationJeong S (2026)
sourceProangiogenic and Collagen-Promoting Effects of a 70% Ethanol Extract of <i>Grateloupia angusta</i> in Cutaneous Wound Models.
topicMarine Collagen Skin Meta-Analysis
claimMarine red algae have been reported to contain a variety of bioactive compounds that are effective in promoting wound-healing processes.
evidence level4
citationJeong S (2026)
sourceProangiogenic and Collagen-Promoting Effects of a 70% Ethanol Extract of <i>Grateloupia angusta</i> in Cutaneous Wound Models.