topicMagnesium Sleep Randomized Trial
claimIt points towards the lack of any analgesic effect of zoledronate, and above all to a latent vulnerability of osteoporotic women who are at a potential risk of fracture with a poor pain modulation that needs to be researched further to limit future chronification.
evidence level2
citationPickering ME (2026)
sourceQuantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation.
topicMagnesium Sleep Randomized Trial
claimBackground Bisphosphonates (BP) are a recommended treatment for osteoporosis and an analgesic effect has been suggested.
evidence level2
citationPickering ME (2026)
sourceQuantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation.
topicMagnesium Sleep Randomized Trial
claimMagnesium is involved in pain mechanisms, mood disorders and also in bone homeostasis.
evidence level2
citationPickering ME (2026)
sourceQuantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation.
topicMagnesium Sleep Randomized Trial
claimFailure to meet the recommended 7-9 hours of restful sleep per night is known to increase the risk of several health conditions, reason why regular and adequate sleep should be seen as a priority instead of an unnecessary commodity easily traded as required by the commitments of our busy lives.
evidence level4
citationConti F (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.
topicMagnesium Sleep Randomized Trial
claimWhile both the quantity and the quality of sleep can be largely improved with relatively straightforward practices dictated by good sleep hygiene, emerging research suggests that dietary and supplementation protocols focused on certain foods, nutrients, and biochemical compounds with sleep-promoting properties can act as subsidiary sleep aids in complementing these behavioral changes.
evidence level4
citationConti F (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.
topicMagnesium Sleep Randomized Trial
claimThe scope of this narrative review is to summarize the available evidence on the potential benefits of selected nutraceuticals in the context of circadian rhythm and sleep disturbances, namely melatonin, magnesium, omega-3 fatty acids, tart cherry juice, kiwifruit, apigenin, valerian root, L-theanine, glycine, ashwagandha, myoinositol, Rhodiola rosea, and phosphatidylserine.
evidence level4
citationConti F (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.
topicMagnesium Sleep Randomized Trial
claimHumans spend approximately one third of their life asleep but, as counterintuitive as it may sound, sleep is far from being a quiet state of inactivity.
evidence level4
citationConti F (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.