topicMagnesium Sleep Randomized Trial
claim1 2 3 4 4 5 6 Postmenopausal osteoporosis is characterized by a diminished bone mineral density, bone microarchitecture changes and an increased fracture risk.
evidence level2
citationPickering Marie-Eva (2026)
sourceQuantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation
topicMagnesium Sleep Randomized Trial
claimBPs may alleviate pain by several mechanisms: action on bone sensory pain fibers and ion channels, peripheral pain sensitization, increased transcription, central sensitization, nerve sprouting and epigenetic modulation [].
evidence level2
citationPickering Marie-Eva (2026)
sourceQuantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation
topicMagnesium Sleep Randomized Trial
claimMore specifically, with zoledronate, after 1 and 2 years of treatment, pain at rest and during standing were improved compared with placebo, especially in patients who sustained incident clinical fractures during the study [].
evidence level2
citationPickering Marie-Eva (2026)
sourceQuantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation
topicMagnesium Sleep Randomized Trial
claimOsteoporosis is often silent and manifests itself especially when a fragility fracture occurs.
evidence level2
citationPickering Marie-Eva (2026)
sourceQuantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation