topicMagnesium Sleep Quality Randomized Trial
claimIt points towards the lack of any analgesic effect of zoledronate, and above all to a latent vulnerability of osteoporotic women who are at a potential risk of fracture with a poor pain modulation that needs to be researched further to limit future chronification.
evidence level2
citationPickering ME (2026)
sourceQuantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation.
topicMagnesium Sleep Quality Randomized Trial
claimBackground Bisphosphonates (BP) are a recommended treatment for osteoporosis and an analgesic effect has been suggested.
evidence level2
citationPickering ME (2026)
sourceQuantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation.
topicMagnesium Sleep Quality Randomized Trial
claimMagnesium is involved in pain mechanisms, mood disorders and also in bone homeostasis.
evidence level2
citationPickering ME (2026)
sourceQuantitative sensory testing of pain in osteoporosis: a pilot randomized clinical trial with magnesium supplementation.
topicMagnesium Sleep Quality Randomized Trial
claimSleep is a complex biological process whose evolutionary purpose has remained equivocal for quite some time.More recently, however, compelling evidence has emerged, leading to recognition of the numerous metabolic and physiological functions sleep contributes to and actively supports.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicMagnesium Sleep Quality Randomized Trial
claimEpidemiological studies have revealed that sleep deprivation is associated with an increased risk of all-cause mortality,alongside numerous chronic conditions imposing a heavy burden on our healthcare and socioeconomic systems alike,including cardiovascular disease, stroke, obesity, type 2 diabetes, and various types of cancer and neurological disorders.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicMagnesium Sleep Quality Randomized Trial
claimThe scope of this narrative review is to summarize the available evidence on the mechanisms of action and potential benefits of the above-listed nutrients in the context of acute or chronic sleep disturbances.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review
topicMagnesium Sleep Quality Randomized Trial
claim, , Over the past few decades, there has been an increasing appreciation of the negative impact of sleep disturbances and circadian misalignments on all aspects of human health and performance, ranging from objective alertness, learning, memory, and cognition to emotional regulation, social wellbeing and, most remarkably, physical health.
evidence level4
citationConti Federica (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review