topicMagnesium Migraine Meta-Analysis
claimOBJECTIVE: To systematically review and synthesize current evidence on sex-related clinical differences in migraine, including treatment outcomes and reproductive management, and to provide evidence-based or expert consensus recommendations where high-quality data are lacking.
evidence level1
citationBraca S (2026)
sourceSex-specific management of migraine a systematic review and consensus statement from the European Headache Federation (EHF).
topicMagnesium Migraine Meta-Analysis
claimTo address anticipated evidence gaps, a structured Delphi consensus process complemented the review.
evidence level1
citationBraca S (2026)
sourceSex-specific management of migraine a systematic review and consensus statement from the European Headache Federation (EHF).
topicMagnesium Migraine Meta-Analysis
claimCONCLUSIONS: Evidence is limited, but sex (likely mediated by sex hormones) influence the clinical course of migraine, and likely treatment response.
evidence level1
citationBraca S (2026)
sourceSex-specific management of migraine a systematic review and consensus statement from the European Headache Federation (EHF).
topicMagnesium Migraine Meta-Analysis
claimAlthough sex differences are recognized in migraine, robust sex-specific guidance for management remains limited.
evidence level1
citationBraca S (2026)
sourceSex-specific management of migraine a systematic review and consensus statement from the European Headache Federation (EHF).
topicMagnesium Migraine Meta-Analysis
claimAssociated symptoms may include nausea, vomiting, photophobia, and phonophobia [].
evidence level3
citationRodriguez Juan Pablo (2025)
sourceMagnesium supplementation for migraine prophylaxis
topicMagnesium Migraine Meta-Analysis
claimHormonal shifts during breastfeeding might also affect migraine occurrence, although the evidence is not definitive [].
evidence level3
citationRodriguez Juan Pablo (2025)
sourceMagnesium supplementation for migraine prophylaxis
topicMagnesium Migraine Meta-Analysis
claimSimilarly, another systematic review found a 7.7% migraine prevalence in this age group, with girls experiencing migraine more often than boys [].
evidence level3
citationRodriguez Juan Pablo (2025)
sourceMagnesium supplementation for migraine prophylaxis
topicMagnesium Migraine Meta-Analysis
claimSecondary headaches are triggered by an existing medical problem, such as issues with blood vessels, tumors, infections, or changes in pressure or volume within the skull.
evidence level3
citationRodriguez Juan Pablo (2025)
sourceMagnesium supplementation for migraine prophylaxis