Lemon Balm Sleep Support Randomized Trial Evidence Table

Structured evidence table for Lemon Balm Sleep Support Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Lemon Balm Sleep Support Randomized TrialResults PSQI scores significantly improved over time ( P P P P Discussion MOP, particularly at 400 mg/day, confirmed to significantly improve sleep and life quality, mood, and overall mental well-being.4Rondanelli M (2026)Melissa phospholipids improves sleep quality and mental well-being: concluding results from clinical study in adults with emotional distress.
Lemon Balm Sleep Support Randomized TrialConclusion These findings support and extend the health benefits of MOP as a well-tolerated, safe natural approach in a dose-dependent frame to managing sleep quality and emotional distress.4Rondanelli M (2026)Melissa phospholipids improves sleep quality and mental well-being: concluding results from clinical study in adults with emotional distress.
Lemon Balm Sleep Support Randomized Trial(lemon balm) is a botanical support widely used for its calming and sleep-promoting properties.4Rondanelli M (2026)Melissa phospholipids improves sleep quality and mental well-being: concluding results from clinical study in adults with emotional distress.
Lemon Balm Sleep Support Randomized TrialObjective To evaluate the impact of daily supplementation with Melissa phospholipids (MOP) at 200 or 400 mg for 3 weeks on sleep quality and psychological well-being in adults with emotional distress and poor sleep quality.4Rondanelli M (2026)Melissa phospholipids improves sleep quality and mental well-being: concluding results from clinical study in adults with emotional distress.
Lemon Balm Sleep Support Randomized TrialA growing body of clinical evidence suggests that MO leaf extract supplementation possesses considerable neuropharmacological properties.4Kara M (2024)An <i>in vitro</i> analysis of an innovative standardized phospholipid carrier-based <i>Melissa officinalis</i> L<i>.</i> extract as a potential neuromodulator for emotional distress and related conditions.
Lemon Balm Sleep Support Randomized TrialRelissa™ demonstrated an improved neuroprotective antioxidant effect on SH-SY5Y cells against H 2 O 2 -induced oxidative stress.4Kara M (2024)An <i>in vitro</i> analysis of an innovative standardized phospholipid carrier-based <i>Melissa officinalis</i> L<i>.</i> extract as a potential neuromodulator for emotional distress and related conditions.
Lemon Balm Sleep Support Randomized TrialMoreover, cell-free chemical tests, including TEAC-ABTS, DPPH radical scavenging, FRAP, ORAC, and HORAC assays, validated the improved antioxidant effect of Relissa™ vs.4Kara M (2024)An <i>in vitro</i> analysis of an innovative standardized phospholipid carrier-based <i>Melissa officinalis</i> L<i>.</i> extract as a potential neuromodulator for emotional distress and related conditions.
Lemon Balm Sleep Support Randomized Trial(MO), commonly known as lemon balm, a member of the mint family, is considered a calming herb.4Kara M (2024)An <i>in vitro</i> analysis of an innovative standardized phospholipid carrier-based <i>Melissa officinalis</i> L<i>.</i> extract as a potential neuromodulator for emotional distress and related conditions.
topicLemon Balm Sleep Support Randomized Trial
claimResults PSQI scores significantly improved over time ( P P P P Discussion MOP, particularly at 400 mg/day, confirmed to significantly improve sleep and life quality, mood, and overall mental well-being.
evidence level4
citationRondanelli M (2026)
sourceMelissa phospholipids improves sleep quality and mental well-being: concluding results from clinical study in adults with emotional distress.
topicLemon Balm Sleep Support Randomized Trial
claimConclusion These findings support and extend the health benefits of MOP as a well-tolerated, safe natural approach in a dose-dependent frame to managing sleep quality and emotional distress.
evidence level4
citationRondanelli M (2026)
sourceMelissa phospholipids improves sleep quality and mental well-being: concluding results from clinical study in adults with emotional distress.
topicLemon Balm Sleep Support Randomized Trial
claim(lemon balm) is a botanical support widely used for its calming and sleep-promoting properties.
evidence level4
citationRondanelli M (2026)
sourceMelissa phospholipids improves sleep quality and mental well-being: concluding results from clinical study in adults with emotional distress.
topicLemon Balm Sleep Support Randomized Trial
claimObjective To evaluate the impact of daily supplementation with Melissa phospholipids (MOP) at 200 or 400 mg for 3 weeks on sleep quality and psychological well-being in adults with emotional distress and poor sleep quality.
evidence level4
citationRondanelli M (2026)
sourceMelissa phospholipids improves sleep quality and mental well-being: concluding results from clinical study in adults with emotional distress.
topicLemon Balm Sleep Support Randomized Trial
claimA growing body of clinical evidence suggests that MO leaf extract supplementation possesses considerable neuropharmacological properties.
evidence level4
citationKara M (2024)
sourceAn <i>in vitro</i> analysis of an innovative standardized phospholipid carrier-based <i>Melissa officinalis</i> L<i>.</i> extract as a potential neuromodulator for emotional distress and related conditions.
topicLemon Balm Sleep Support Randomized Trial
claimRelissa™ demonstrated an improved neuroprotective antioxidant effect on SH-SY5Y cells against H 2 O 2 -induced oxidative stress.
evidence level4
citationKara M (2024)
sourceAn <i>in vitro</i> analysis of an innovative standardized phospholipid carrier-based <i>Melissa officinalis</i> L<i>.</i> extract as a potential neuromodulator for emotional distress and related conditions.
topicLemon Balm Sleep Support Randomized Trial
claimMoreover, cell-free chemical tests, including TEAC-ABTS, DPPH radical scavenging, FRAP, ORAC, and HORAC assays, validated the improved antioxidant effect of Relissa™ vs.
evidence level4
citationKara M (2024)
sourceAn <i>in vitro</i> analysis of an innovative standardized phospholipid carrier-based <i>Melissa officinalis</i> L<i>.</i> extract as a potential neuromodulator for emotional distress and related conditions.
topicLemon Balm Sleep Support Randomized Trial
claim(MO), commonly known as lemon balm, a member of the mint family, is considered a calming herb.
evidence level4
citationKara M (2024)
sourceAn <i>in vitro</i> analysis of an innovative standardized phospholipid carrier-based <i>Melissa officinalis</i> L<i>.</i> extract as a potential neuromodulator for emotional distress and related conditions.

Source documents

  1. Melissa phospholipids improves sleep quality and mental well-being: concluding results from clinical study in adults with emotional distress.
  2. An <i>in vitro</i> analysis of an innovative standardized phospholipid carrier-based <i>Melissa officinalis</i> L<i>.</i> extract as a potential neuromodulator for emotional distress and related conditions.