L-Theanine Cognitive Performance Meta-Analysis Evidence Table

Structured evidence table for L-Theanine Cognitive Performance Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
L-Theanine Cognitive Performance Meta-AnalysisCamellia sinensis Coffea arabica Camellia sinensis Paullinia cupana 1 2 3 3 3 4 3 5 l l Green tea () is an evergreen plant found mainly in the tropical and temperate regions of Asia, especially in China, Srí Lanka, Japan and India, and it has been consumed for centuries as food and for its beneficial effects on human health [,,].1Mátyus Rebeka Olga (2025)Promising, but Not Completely Conclusive—The Effect of l -Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials
L-Theanine Cognitive Performance Meta-AnalysisBased on preclinical and clinical evidence, caffeine and-theanine are the two main constituents contributing to this effect [].1Mátyus Rebeka Olga (2025)Promising, but Not Completely Conclusive—The Effect of l -Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials
L-Theanine Cognitive Performance Meta-AnalysisCaffeine is a stimulant compound belonging to the group of methylxanthines and is found in several plants, including(coffee),and(guarana) [,].1Mátyus Rebeka Olga (2025)Promising, but Not Completely Conclusive—The Effect of l -Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials
L-Theanine Cognitive Performance Meta-AnalysisThe main constituents of the leaves are polyphenols, but other components such as methylxanthine derivatives (caffeine, theobromine, theophylline), organic acids, flavonoids, free amino acids (such as-theanine) and several flavor components are also present in fresh leaves [].1Mátyus Rebeka Olga (2025)Promising, but Not Completely Conclusive—The Effect of l -Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials
L-Theanine Cognitive Performance Meta-AnalysisBy synthesizing molecular evidence from the BDNF/TrkB/CREB signaling axis and the Nrf2/NF-κB homeostatic switch, we demonstrate that this multi-target strategy offers a more robust path to neuronal resilience than traditional single-target approaches.4Cipriano GL (2026)Phytochemical and Fungal Bioactive Compounds in the "Brain Health Triad": A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy.
L-Theanine Cognitive Performance Meta-AnalysisThis narrative review proposes the 'Brain Health Triad' as a novel integrative framework for neurorehabilitation and cognitive enhancement, built upon three interdependent biological pillars: neurostimulation, neurotrophy, and neuroprotection.4Cipriano GL (2026)Phytochemical and Fungal Bioactive Compounds in the "Brain Health Triad": A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy.
L-Theanine Cognitive Performance Meta-AnalysisWe illustrate how the synergistic interplay between a 'core triad' composed of Hericium erinaceus , Bacopa monnieri , and L-Theanine targets these pillars with high specificity.4Cipriano GL (2026)Phytochemical and Fungal Bioactive Compounds in the "Brain Health Triad": A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy.
topicL-Theanine Cognitive Performance Meta-Analysis
claimCamellia sinensis Coffea arabica Camellia sinensis Paullinia cupana 1 2 3 3 3 4 3 5 l l Green tea () is an evergreen plant found mainly in the tropical and temperate regions of Asia, especially in China, Srí Lanka, Japan and India, and it has been consumed for centuries as food and for its beneficial effects on human health [,,].
evidence level1
citationMátyus Rebeka Olga (2025)
sourcePromising, but Not Completely Conclusive—The Effect of l -Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials
topicL-Theanine Cognitive Performance Meta-Analysis
claimBased on preclinical and clinical evidence, caffeine and-theanine are the two main constituents contributing to this effect [].
evidence level1
citationMátyus Rebeka Olga (2025)
sourcePromising, but Not Completely Conclusive—The Effect of l -Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials
topicL-Theanine Cognitive Performance Meta-Analysis
claimCaffeine is a stimulant compound belonging to the group of methylxanthines and is found in several plants, including(coffee),and(guarana) [,].
evidence level1
citationMátyus Rebeka Olga (2025)
sourcePromising, but Not Completely Conclusive—The Effect of l -Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials
topicL-Theanine Cognitive Performance Meta-Analysis
claimThe main constituents of the leaves are polyphenols, but other components such as methylxanthine derivatives (caffeine, theobromine, theophylline), organic acids, flavonoids, free amino acids (such as-theanine) and several flavor components are also present in fresh leaves [].
evidence level1
citationMátyus Rebeka Olga (2025)
sourcePromising, but Not Completely Conclusive—The Effect of l -Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials
topicL-Theanine Cognitive Performance Meta-Analysis
claimBy synthesizing molecular evidence from the BDNF/TrkB/CREB signaling axis and the Nrf2/NF-κB homeostatic switch, we demonstrate that this multi-target strategy offers a more robust path to neuronal resilience than traditional single-target approaches.
evidence level4
citationCipriano GL (2026)
sourcePhytochemical and Fungal Bioactive Compounds in the "Brain Health Triad": A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy.
topicL-Theanine Cognitive Performance Meta-Analysis
claimThis narrative review proposes the 'Brain Health Triad' as a novel integrative framework for neurorehabilitation and cognitive enhancement, built upon three interdependent biological pillars: neurostimulation, neurotrophy, and neuroprotection.
evidence level4
citationCipriano GL (2026)
sourcePhytochemical and Fungal Bioactive Compounds in the "Brain Health Triad": A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy.
topicL-Theanine Cognitive Performance Meta-Analysis
claimWe illustrate how the synergistic interplay between a 'core triad' composed of Hericium erinaceus , Bacopa monnieri , and L-Theanine targets these pillars with high specificity.
evidence level4
citationCipriano GL (2026)
sourcePhytochemical and Fungal Bioactive Compounds in the "Brain Health Triad": A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy.

Source documents

  1. Promising, but Not Completely Conclusive—The Effect of l -Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials
  2. Phytochemical and Fungal Bioactive Compounds in the "Brain Health Triad": A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy.