Hydrolyzed Collagen Skin Meta-Analysis Evidence Table

Structured evidence table for Hydrolyzed Collagen Skin Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Hydrolyzed Collagen Skin Meta-AnalysisIntroduction Skin aging manifests as wrinkles, reduced elasticity, and roughness due to intrinsic and extrinsic factors.1Nukaly HY (2026)Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
Hydrolyzed Collagen Skin Meta-AnalysisPeptides, particularly oral formulations, significantly improved hydration and brightness, with a modest pooled effect on wrinkle reduction (MD = 0.27, p = 0.04).1Nukaly HY (2026)Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
Hydrolyzed Collagen Skin Meta-AnalysisPeptide-based therapies enhance collagen synthesis and extracellular matrix integrity.1Nukaly HY (2026)Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
Hydrolyzed Collagen Skin Meta-AnalysisResults Supplementation with 10 g/day of BCP significantly reduced the number (p Conclusions A 12-week course of Peptpure ® BCP supplementation improved facial skin health, underlined by increased systemic levels of TGF-β and Klotho, suggesting activation of regenerative and antiaging pathways.4Paula-Vieira RHR (2026)Immune-Modulatory Effects of Bioactive Collagen Peptides Improve Skin Health in Middle-Aged Women.
Hydrolyzed Collagen Skin Meta-AnalysisIntroduction Collagen peptides are widely used to support skin health, but the immunological mechanisms mediating such effects remain unclear.4Paula-Vieira RHR (2026)Immune-Modulatory Effects of Bioactive Collagen Peptides Improve Skin Health in Middle-Aged Women.
Hydrolyzed Collagen Skin Meta-AnalysisSo, this study investigated the effects of bioactive collagen peptide (BCP) supplementation on facial wrinkles, skin biophysical properties, and systemic levels of transforming growth factor-beta (TGF-β) and Klotho in sedentary middle-aged women.4Paula-Vieira RHR (2026)Immune-Modulatory Effects of Bioactive Collagen Peptides Improve Skin Health in Middle-Aged Women.
topicHydrolyzed Collagen Skin Meta-Analysis
claimIntroduction Skin aging manifests as wrinkles, reduced elasticity, and roughness due to intrinsic and extrinsic factors.
evidence level1
citationNukaly HY (2026)
sourceOral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
topicHydrolyzed Collagen Skin Meta-Analysis
claimPeptides, particularly oral formulations, significantly improved hydration and brightness, with a modest pooled effect on wrinkle reduction (MD = 0.27, p = 0.04).
evidence level1
citationNukaly HY (2026)
sourceOral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
topicHydrolyzed Collagen Skin Meta-Analysis
claimPeptide-based therapies enhance collagen synthesis and extracellular matrix integrity.
evidence level1
citationNukaly HY (2026)
sourceOral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
topicHydrolyzed Collagen Skin Meta-Analysis
claimResults Supplementation with 10 g/day of BCP significantly reduced the number (p Conclusions A 12-week course of Peptpure ® BCP supplementation improved facial skin health, underlined by increased systemic levels of TGF-β and Klotho, suggesting activation of regenerative and antiaging pathways.
evidence level4
citationPaula-Vieira RHR (2026)
sourceImmune-Modulatory Effects of Bioactive Collagen Peptides Improve Skin Health in Middle-Aged Women.
topicHydrolyzed Collagen Skin Meta-Analysis
claimIntroduction Collagen peptides are widely used to support skin health, but the immunological mechanisms mediating such effects remain unclear.
evidence level4
citationPaula-Vieira RHR (2026)
sourceImmune-Modulatory Effects of Bioactive Collagen Peptides Improve Skin Health in Middle-Aged Women.
topicHydrolyzed Collagen Skin Meta-Analysis
claimSo, this study investigated the effects of bioactive collagen peptide (BCP) supplementation on facial wrinkles, skin biophysical properties, and systemic levels of transforming growth factor-beta (TGF-β) and Klotho in sedentary middle-aged women.
evidence level4
citationPaula-Vieira RHR (2026)
sourceImmune-Modulatory Effects of Bioactive Collagen Peptides Improve Skin Health in Middle-Aged Women.

Source documents

  1. Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
  2. Immune-Modulatory Effects of Bioactive Collagen Peptides Improve Skin Health in Middle-Aged Women.