Structured evidence table for Hyaluronic Joint Pain Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Hyaluronic Joint Pain Meta-Analysis | An ageing population, rising obesity rates, and increased recreational sports activity have contributed to a higher prevalence of this degenerative disease. | 1 | Ventura-García María Ángeles (2026) | Efficacy and Safety of Platelet-Rich Plasma in Knee Osteoarthritis: Umbrella Meta-Analysis Based on Clinical Evidence, Methodological Quality and Therapeutic Positioning |
| Hyaluronic Joint Pain Meta-Analysis | The umbrella meta-analysis, which synthesizes the results of existing meta-analyses, provides an overview of the available evidence at the highest hierarchical level []. | 1 | Ventura-García María Ángeles (2026) | Efficacy and Safety of Platelet-Rich Plasma in Knee Osteoarthritis: Umbrella Meta-Analysis Based on Clinical Evidence, Methodological Quality and Therapeutic Positioning |
| Hyaluronic Joint Pain Meta-Analysis | 8 Despite the clinical promise of PRP, the current landscape is characterized by a high volume of secondary evidence with conflicting results, often due to differences in methodological quality and primary study overlap []. | 1 | Ventura-García María Ángeles (2026) | Efficacy and Safety of Platelet-Rich Plasma in Knee Osteoarthritis: Umbrella Meta-Analysis Based on Clinical Evidence, Methodological Quality and Therapeutic Positioning |
| Hyaluronic Joint Pain Meta-Analysis | 1 2 Knee osteoarthritis (KOA) is one of the leading causes of disability worldwide and poses a growing challenge to healthcare systems []. | 1 | Ventura-García María Ángeles (2026) | Efficacy and Safety of Platelet-Rich Plasma in Knee Osteoarthritis: Umbrella Meta-Analysis Based on Clinical Evidence, Methodological Quality and Therapeutic Positioning |
| Hyaluronic Joint Pain Meta-Analysis | To ensure a robust synthesis of evidence, we conducted a systematic search of PubMed, Embase, and Web of Science (2020-2025) for high-quality clinical trials, meta-analyses, and guidelines. | 4 | Wang H (2026) | Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions. |
| Hyaluronic Joint Pain Meta-Analysis | This narrative review evaluates the clinical transition from reactive, surgery-centric models to a proactive, integrated framework to mitigate the profound socioeconomic burden and functional decline associated with the disease. | 4 | Wang H (2026) | Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions. |
| Hyaluronic Joint Pain Meta-Analysis | We synthesized evidence across non-pharmacological rehabilitation, pharmacotherapy, and advanced joint-preserving surgeries, emphasizing optimal intervention windows and stage-specific mechanobiological requirements. | 4 | Wang H (2026) | Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions. |
| Hyaluronic Joint Pain Meta-Analysis | Knee osteoarthritis (KOA) is a primary driver of global disability, currently affecting over 365 million adults, with projections suggesting a 74.9% increase by 2050. | 4 | Wang H (2026) | Evolving Strategies for Knee Osteoarthritis: A Narrative Review of Integrated Rehabilitation, Pharmacologic, and Joint-Preserving Interventions. |
Source documents