evidence table
Hyaluronic Acid Skin Randomized Trial Evidence Table
Structured evidence table for Hyaluronic Acid Skin Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Hyaluronic Acid Skin Randomized Trial | According to Merz scores before and 3 months after treatment, the wrinkles were dramatically reduced in both groups ( p value: p value: 0.633). | 2 | Saffarian Z (2026) | Combined Use of Botulinum Toxin A and Profhilo for Upper Face Rejuvenation: A Randomized Clinical Trial. |
| Hyaluronic Acid Skin Randomized Trial | Conclusion We have shown that adding Profhilo to BTX-A injection does not have any short-term clinical or sonographic advantage in frontal area wrinkle reduction. | 2 | Saffarian Z (2026) | Combined Use of Botulinum Toxin A and Profhilo for Upper Face Rejuvenation: A Randomized Clinical Trial. |
| Hyaluronic Acid Skin Randomized Trial | Background Hyaluronic acid (HA) and Botulinum toxin A (BTX-A) treatments are highly regarded for their effectiveness in facial rejuvenation. | 2 | Saffarian Z (2026) | Combined Use of Botulinum Toxin A and Profhilo for Upper Face Rejuvenation: A Randomized Clinical Trial. |
| Hyaluronic Acid Skin Randomized Trial | Aim To investigate whether adding Profhilo enhances the effects of BTX-A for frontal skin rejuvenation. | 2 | Saffarian Z (2026) | Combined Use of Botulinum Toxin A and Profhilo for Upper Face Rejuvenation: A Randomized Clinical Trial. |
| Hyaluronic Acid Skin Randomized Trial | Hydration increased steadily in the treatment group, exceeding that of the control at all post-treatment time points (P Conclusion Full‑face intradermal NCHA improved skin hydration, elasticity, texture, and fine lines with a favorable safety profile. | 2 | Cheng H (2026) | A Prospective, Multicenter, Randomized, Assessor-Blinded Study Assessing the Efficacy and Safety of Injectable Non-Cross-Linked Hyaluronic Acid for Improving Facial Skin Rejuvenation. |
| Hyaluronic Acid Skin Randomized Trial | Objective To evaluate the efficacy and safety of an injectable non-cross-linked hyaluronic acid (NCHA) solution in improving facial skin appearance. | 2 | Cheng H (2026) | A Prospective, Multicenter, Randomized, Assessor-Blinded Study Assessing the Efficacy and Safety of Injectable Non-Cross-Linked Hyaluronic Acid for Improving Facial Skin Rejuvenation. |
| Hyaluronic Acid Skin Randomized Trial | Methods This prospective, multicenter, randomized, no‑treatment-controlled, assessor-blinded, superiority clinical trial was conducted from December 2023 to July 2024 with 448 adults (224 per arm). | 2 | Cheng H (2026) | A Prospective, Multicenter, Randomized, Assessor-Blinded Study Assessing the Efficacy and Safety of Injectable Non-Cross-Linked Hyaluronic Acid for Improving Facial Skin Rejuvenation. |
Source documents