evidence table

Hyaluronic Acid Skin Aging Randomized Trial Evidence Table

Structured evidence table for Hyaluronic Acid Skin Aging Randomized Trial, generated from 1 reusable source document in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Hyaluronic Acid Skin Aging Randomized TrialIn accordance with EMA Committee for Advanced Therapies (EMA-CAT) recommendations (Guideline on Human Cell-Based Medicinal Products, 2015, section 2.2.4a), this approach qualifies as a “technique, since the processing does not alter the biological characteristics, physiological functions, or structural properties of the cells.2Gentile Pietro (2026)Autologous fibroblast therapy for facial rejuvenation: A randomized open-label controlled study
Hyaluronic Acid Skin Aging Randomized Trial20 patients with mild to moderate dermal thinning, reduced elasticity, and wrinkles were assigned to the study group (SG) and treated with Am-FBs (A–C).2Gentile Pietro (2026)Autologous fibroblast therapy for facial rejuvenation: A randomized open-label controlled study
Hyaluronic Acid Skin Aging Randomized TrialThe Risk Evaluation and Mitigation Strategies (REMSs) incorporating Elements to Assure Safe Use (ETASU) were applied in Am-FBs and HA-based skin booster treatments, significantly reducing safety-related risks.2Gentile Pietro (2026)Autologous fibroblast therapy for facial rejuvenation: A randomized open-label controlled study
Hyaluronic Acid Skin Aging Randomized Trial, , , The natural aging process leads to the degradation of the dermal extracellular matrix (ECM), decreased fibroblast activity, and a loss of skin elasticity.Traditional cosmetic procedures, such as hyaluronic acid (HA)-based skin boosters, provide temporary benefits, but autologous cell-based therapies offer a biologically driven regenerative approach.2Gentile Pietro (2026)Autologous fibroblast therapy for facial rejuvenation: A randomized open-label controlled study
topicHyaluronic Acid Skin Aging Randomized Trial
claimIn accordance with EMA Committee for Advanced Therapies (EMA-CAT) recommendations (Guideline on Human Cell-Based Medicinal Products, 2015, section 2.2.4a), this approach qualifies as a “technique, since the processing does not alter the biological characteristics, physiological functions, or structural properties of the cells.
evidence level2
citationGentile Pietro (2026)
sourceAutologous fibroblast therapy for facial rejuvenation: A randomized open-label controlled study
topicHyaluronic Acid Skin Aging Randomized Trial
claim20 patients with mild to moderate dermal thinning, reduced elasticity, and wrinkles were assigned to the study group (SG) and treated with Am-FBs (A–C).
evidence level2
citationGentile Pietro (2026)
sourceAutologous fibroblast therapy for facial rejuvenation: A randomized open-label controlled study
topicHyaluronic Acid Skin Aging Randomized Trial
claimThe Risk Evaluation and Mitigation Strategies (REMSs) incorporating Elements to Assure Safe Use (ETASU) were applied in Am-FBs and HA-based skin booster treatments, significantly reducing safety-related risks.
evidence level2
citationGentile Pietro (2026)
sourceAutologous fibroblast therapy for facial rejuvenation: A randomized open-label controlled study
topicHyaluronic Acid Skin Aging Randomized Trial
claim, , , The natural aging process leads to the degradation of the dermal extracellular matrix (ECM), decreased fibroblast activity, and a loss of skin elasticity.Traditional cosmetic procedures, such as hyaluronic acid (HA)-based skin boosters, provide temporary benefits, but autologous cell-based therapies offer a biologically driven regenerative approach.
evidence level2
citationGentile Pietro (2026)
sourceAutologous fibroblast therapy for facial rejuvenation: A randomized open-label controlled study

Learn next

Related evidence and supplement guides

SupplementL-TheanineA unique amino acid primarily found in green tea leaves that promotes relaxation, quietens menta...SupplementCollagenThe primary structural protein in the body, essential for skin elasticity, joint health, and str...SupplementAlpha-Lipoic AcidUniversal antioxidant that regenerates vitamins C and E, and improves insulin sensitivity.GuideHyaluronic Acid Skin Aging Randomized Trial: What the Evidence SaysHyaluronic Acid Skin Aging Randomized Trial has 1 source documents in the current Migaku evidenc...GuideHyaluronic Acid Skin Health Randomized Trial: What the Evidence SaysHyaluronic Acid Skin Health Randomized Trial has 2 source documents in the current Migaku eviden...GuideHyaluronic Skin Aging Randomized Trial: What the Evidence SaysHyaluronic Skin Aging Randomized Trial has 2 source documents in the current Migaku evidence dat...GuideHyaluronic Acid Skin Hydration Randomized Trial: What the Evidence SaysHyaluronic Acid Skin Hydration Randomized Trial has 2 source documents in the current Migaku evi...RankingBest Collagen for Hair, Skin & Nails: 2026 Evidence-Based RankingsWe analyzed the amino acid concentrations and molecular weights of top collagen brands to identi...

Source documents

  1. Autologous fibroblast therapy for facial rejuvenation: A randomized open-label controlled study