topicHyaluronic Acid Joint Health Randomized Trial
claim25 37 13 5 Hip OA is a major cause of pain, leading to significant mobility limitations, reduced physical capacity and severe impact on the patient's quality of life.
evidence level2
citationde Sire Alessandro (2026)
sourceCombined ultrasound‐guided hyaluronic acid injections, high‐power laser therapy and physiotherapy improve hip function in osteoarthritis: A randomized controlled trial
topicHyaluronic Acid Joint Health Randomized Trial
claimHowever, the literature offers few studies, and those available present conflicting results regarding postural changes associated with hip joint damage [].
evidence level2
citationde Sire Alessandro (2026)
sourceCombined ultrasound‐guided hyaluronic acid injections, high‐power laser therapy and physiotherapy improve hip function in osteoarthritis: A randomized controlled trial
topicHyaluronic Acid Joint Health Randomized Trial
claimPatients with BMI > 30 were excluded to avoid confounding factors related to excessive mechanical load and reduced rehabilitation adherence; suspension of anti‐inflammatory drugs (NSAIDs), opioids, corticosteroids, muscle relaxants or any other therapy that could interfere with the study assessments.
evidence level2
citationde Sire Alessandro (2026)
sourceCombined ultrasound‐guided hyaluronic acid injections, high‐power laser therapy and physiotherapy improve hip function in osteoarthritis: A randomized controlled trial
topicHyaluronic Acid Joint Health Randomized Trial
claim28 13 41 The hip joint is one of the primary joints commonly affected by degenerative osteoarthritis (OA) [].
evidence level2
citationde Sire Alessandro (2026)
sourceCombined ultrasound‐guided hyaluronic acid injections, high‐power laser therapy and physiotherapy improve hip function in osteoarthritis: A randomized controlled trial
topicHyaluronic Acid Joint Health Randomized Trial
claimThese findings provided high-level evidence challenging the clinical benefit of cross-linked HAs.
evidence level2
citationKanitnate S (2026)
sourceEfficacy of Ultra-high and High Molecular Weight Cross-Linked Hyaluronic Acids Compared with Saline in Knee Osteoarthritis: A Randomized Controlled Trial.
topicHyaluronic Acid Joint Health Randomized Trial
claimIntroduction Intra-articular hyaluronic acid (HA) injections are widely used for knee osteoarthritis (OA) to reduce pain and improve function.
evidence level2
citationKanitnate S (2026)
sourceEfficacy of Ultra-high and High Molecular Weight Cross-Linked Hyaluronic Acids Compared with Saline in Knee Osteoarthritis: A Randomized Controlled Trial.
topicHyaluronic Acid Joint Health Randomized Trial
claimThis study aimed to compare the efficacy of 2 single-injection, ultra-high, and high molecular weight (HMW) cross-linked HAs against a saline placebo for symptomatic knee OA.
evidence level2
citationKanitnate S (2026)
sourceEfficacy of Ultra-high and High Molecular Weight Cross-Linked Hyaluronic Acids Compared with Saline in Knee Osteoarthritis: A Randomized Controlled Trial.