Structured evidence table for Glycine Exercise Performance Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Glycine Exercise Performance Randomized Trial | Out of those, three measured the effect of an acute supplementation, and three described the effect of a chronic supplementation, but no significant improvements on performance were found. | 1 | Mielgo-Ayuso J (2021) | Effect of Acute and Chronic Oral l-Carnitine Supplementation on Exercise Performance Based on the Exercise Intensity: A Systematic Review. |
| Glycine Exercise Performance Randomized Trial | In summary, l-C supplementation with 3 to 4 g ingested between 60 and 90 min before testing or 2 to 2.72 g/day for 9 to 24 weeks improved high-intensity exercise performance. | 1 | Mielgo-Ayuso J (2021) | Effect of Acute and Chronic Oral l-Carnitine Supplementation on Exercise Performance Based on the Exercise Intensity: A Systematic Review. |
| Glycine Exercise Performance Randomized Trial | l-Carnitine (l-C) and any of its forms (glycine-propionyl l-Carnitine (GPL-C) or l-Carnitine l-tartrate (l-CLT)) has been frequently recommended as a supplement to improve sports performance due to, among others, its role in fat metabolism and in maintaining the mitochondrial acetyl-CoA/CoA ratio. | 1 | Mielgo-Ayuso J (2021) | Effect of Acute and Chronic Oral l-Carnitine Supplementation on Exercise Performance Based on the Exercise Intensity: A Systematic Review. |
| Glycine Exercise Performance Randomized Trial | The main aim of the present systematic review was to determine the effects of oral l-C supplementation on moderate- (50-79% V˙O 2 max ) and high-intensity (≥80% V˙O 2 max ) exercise performance and to show the effective doses and ideal timing of its intake. | 1 | Mielgo-Ayuso J (2021) | Effect of Acute and Chronic Oral l-Carnitine Supplementation on Exercise Performance Based on the Exercise Intensity: A Systematic Review. |
| Glycine Exercise Performance Randomized Trial | We found that TMAO pre-administration markedly prolonged the exhaustive time in mice. | 4 | Zou H (2024) | Effects of Trimethylamine N-Oxide in Improving Exercise Performance in Mice: A <sup>1</sup>H-NMR-Based Metabolomic Analysis Approach. |
| Glycine Exercise Performance Randomized Trial | Further investigation showed that TMAO pre-administration increased levels of 3-hydroxybutyrate, isocitrate, anserine, TMA, taurine, glycine, and glutathione and disturbed the three metabolic pathways related to oxidative stress and protein synthesis in skeletal muscle. | 4 | Zou H (2024) | Effects of Trimethylamine N-Oxide in Improving Exercise Performance in Mice: A <sup>1</sup>H-NMR-Based Metabolomic Analysis Approach. |
| Glycine Exercise Performance Randomized Trial | To improve exercise performance, the supplement of nutrients has become a common practice before prolonged exercise. | 4 | Zou H (2024) | Effects of Trimethylamine N-Oxide in Improving Exercise Performance in Mice: A <sup>1</sup>H-NMR-Based Metabolomic Analysis Approach. |
| Glycine Exercise Performance Randomized Trial | Trimethylamine N-oxide (TMAO) has been shown to ameliorate oxidative stress damage, which may be beneficial in improving exercise capacity. | 4 | Zou H (2024) | Effects of Trimethylamine N-Oxide in Improving Exercise Performance in Mice: A <sup>1</sup>H-NMR-Based Metabolomic Analysis Approach. |
Source documents