topicGlycine Cognition Meta-Analysis
claimBackground Social cognitive impairments are a fundamental aspect of schizophrenia, exerting a substantial influence on patients' functional outcomes.
evidence level1
citationYamada Y (2026)
sourcePharmacological interventions for social cognitive impairments in schizophrenia: A systematic review and network meta-analysis of randomized controlled trials.
topicGlycine Cognition Meta-Analysis
claimHowever, to date, there have been no meta-analyses of comprehensive pharmacological interventions covering all domains of social cognition.
evidence level1
citationYamada Y (2026)
sourcePharmacological interventions for social cognitive impairments in schizophrenia: A systematic review and network meta-analysis of randomized controlled trials.
topicGlycine Cognition Meta-Analysis
claim[ ] 7 8 Preclinical and clinical evidence indicate that cisplatin can cross the blood–brain barrier and accumulates in brain regions critical for learning and memory, particularly the hippocampus and prefrontal cortex.
evidence level4
citationKazmi Hafiz Muhammad Obaid (2026)
sourceNeuroprotective effects of glycine against cisplatin-induced cognitive decline in mice
topicGlycine Cognition Meta-Analysis
claimThese molecular and cellular changes translate into impaired synaptic plasticity, reduced neurogenesis, and deficits in spatial learning and memory on standard behavioral tests,.
evidence level4
citationKazmi Hafiz Muhammad Obaid (2026)
sourceNeuroprotective effects of glycine against cisplatin-induced cognitive decline in mice
topicGlycine Cognition Meta-Analysis
claimWe hypothesize that glycine administration will ameliorate cisplatin-associated deficits in spatial learning and working memory and that behavioral protection will align with reduced inflammatory signaling and preserved neuronal integrity.
evidence level4
citationKazmi Hafiz Muhammad Obaid (2026)
sourceNeuroprotective effects of glycine against cisplatin-induced cognitive decline in mice
topicGlycine Cognition Meta-Analysis
claim[ ] 1 2 Cisplatin, cis-diamminedichloroplatinum II, is one of the most widely used platinum-based chemotherapeutic agents, and it remains a cornerstone treatment for multiple solid tumors including testicular, ovarian, head and neck, lung, and bladder cancers.
evidence level4
citationKazmi Hafiz Muhammad Obaid (2026)
sourceNeuroprotective effects of glycine against cisplatin-induced cognitive decline in mice