Structured evidence table for Dha Cognition Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Dha Cognition Meta-Analysis | Concurrently, the number of individuals affected by dementia is anticipated to nearly triple by 2050, with associated treatment costs projected to reach US$2.8 trillion by 2030 []. | 1 | Liu Xing (2026) | Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis |
| Dha Cognition Meta-Analysis | In addition, omega-3 fatty acids support synaptic plasticity and exert anti-inflammatory effects; however, evidence is mixed, as randomized trials in healthy older adults show limited benefits [,], while several analyses report modest improvements in aged or MCI patients [,]. | 1 | Liu Xing (2026) | Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis |
| Dha Cognition Meta-Analysis | Observational studies and recent trials involving antioxidant nutrients, such as pomegranate juice and resveratrol, alongside polyphenols, suggest potential protection for specific cognitive domains (e.g., memory) and reduced dementia risk, although effects are heterogeneous and causality remains unconfirmed [,]. | 1 | Liu Xing (2026) | Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis |
| Dha Cognition Meta-Analysis | 1 2 3 4 5 6 7 8 9 10 The World Health Organization (WHO) projects that by 2050, the global population aged 60 and above will reach 2.1 billion, highlighting the inevitability of global aging []. | 1 | Liu Xing (2026) | Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis |
| Dha Cognition Meta-Analysis | Despite its biological relevance, global evidence indicates substantial variability in DHA intake and status, largely influenced by dietary patterns, food availability, and socioeconomic conditions. | 4 | Valle-Valdez B (2026) | Docosahexaenoic acid intake and health in adults and older adults: a narrative review of disparities by country income level. |
| Dha Cognition Meta-Analysis | Populations in high-income countries (HICs) generally reported higher DHA intake and tissue concentrations, mainly due to regular fish consumption and greater access to supplementation, while evidence from middle-income countries (MICs) was scarce, heterogeneous, and based on small non-representative samples. | 4 | Valle-Valdez B (2026) | Docosahexaenoic acid intake and health in adults and older adults: a narrative review of disparities by country income level. |
| Dha Cognition Meta-Analysis | In HICs, even moderate fish intake significantly improved DHA status, whereas in MICs, mean intakes frequently fell below 200 mg/day, a threshold commonly associated with cardiometabolic and neurocognitive benefits. | 4 | Valle-Valdez B (2026) | Docosahexaenoic acid intake and health in adults and older adults: a narrative review of disparities by country income level. |
| Dha Cognition Meta-Analysis | Docosahexaenoic acid (DHA) is a long-chain omega-3 polyunsaturated fatty acid essential for maintaining optimal brain and cardiometabolic health across adulthood and aging. | 4 | Valle-Valdez B (2026) | Docosahexaenoic acid intake and health in adults and older adults: a narrative review of disparities by country income level. |
Source documents