Structured evidence table for Curcumin Sleep Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Curcumin Sleep Randomized Trial | 7 8 9 10 11 12 13 Pathophysiology has revealed that one of the primary risk factors for depression is chronic stress due to glucocorticoid effects on the hypothalamic–pituitary–adrenal (HPA) axis []. | 2 | Cavanah Aidan M. (2026) | A Randomized Controlled Trial to Determine the Effects of Curcumin and Epigallocatechin-3-Gallate Supplementation on Serum Brain-Derived Neurotrophic Factor and Mood Disturbance in Adults |
| Curcumin Sleep Randomized Trial | BDNF exerts neuroprotective and neuroactivating properties on both excitatory and inhibitory neurons, with high concentrations found in the hippocampus and frontal cortex []. | 2 | Cavanah Aidan M. (2026) | A Randomized Controlled Trial to Determine the Effects of Curcumin and Epigallocatechin-3-Gallate Supplementation on Serum Brain-Derived Neurotrophic Factor and Mood Disturbance in Adults |
| Curcumin Sleep Randomized Trial | These studies support the ‘neurotrophin hypothesis of depression’, which states that reduced levels of BDNF in the brain contribute to cell atrophy in the hippocampus and prefrontal cortex []. | 2 | Cavanah Aidan M. (2026) | A Randomized Controlled Trial to Determine the Effects of Curcumin and Epigallocatechin-3-Gallate Supplementation on Serum Brain-Derived Neurotrophic Factor and Mood Disturbance in Adults |
| Curcumin Sleep Randomized Trial | 1 2 3 4 5 6 Mood disorders are notable disruptions in emotions that occur internally but can impact a person’s behavior externally []. | 2 | Cavanah Aidan M. (2026) | A Randomized Controlled Trial to Determine the Effects of Curcumin and Epigallocatechin-3-Gallate Supplementation on Serum Brain-Derived Neurotrophic Factor and Mood Disturbance in Adults |
| Curcumin Sleep Randomized Trial | Background Diabetic retinopathy (DR) is a significant complication of diabetes that can adversely affect the quality of life and anthropometric indices of individuals. | 2 | Amini S (2026) | The Effect of Curcumin Plus Piperine on Mental Health Status, Sleep Quality, and Anthropometric Indices in Patients with Non-Proliferative Diabetic Retinopathy: A Randomized Double-Blind Placebo-Controlled Trial. |
| Curcumin Sleep Randomized Trial | This study aimed to investigate the impact of a combination of curcumin and piperine on mental health status (stress, anxiety, and depression), sleep quality, and anthropometric indices in patients with non-proliferative diabetic retinopathy. | 2 | Amini S (2026) | The Effect of Curcumin Plus Piperine on Mental Health Status, Sleep Quality, and Anthropometric Indices in Patients with Non-Proliferative Diabetic Retinopathy: A Randomized Double-Blind Placebo-Controlled Trial. |
Source documents