evidence table
Curcumin Depression Meta-Analysis Evidence Table
Structured evidence table for Curcumin Depression Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Curcumin Depression Meta-Analysis | Background Diabetic retinopathy (DR) is a significant complication of diabetes that can adversely affect the quality of life and anthropometric indices of individuals. | 2 | Amini S (2026) | The Effect of Curcumin Plus Piperine on Mental Health Status, Sleep Quality, and Anthropometric Indices in Patients with Non-Proliferative Diabetic Retinopathy: A Randomized Double-Blind Placebo-Controlled Trial. |
| Curcumin Depression Meta-Analysis | This study aimed to investigate the impact of a combination of curcumin and piperine on mental health status (stress, anxiety, and depression), sleep quality, and anthropometric indices in patients with non-proliferative diabetic retinopathy. | 2 | Amini S (2026) | The Effect of Curcumin Plus Piperine on Mental Health Status, Sleep Quality, and Anthropometric Indices in Patients with Non-Proliferative Diabetic Retinopathy: A Randomized Double-Blind Placebo-Controlled Trial. |
| Curcumin Depression Meta-Analysis | This literature review synthesises evidence from randomised controlled trials, meta-analyses, safety data, dosing patterns, proposed mechanisms, and guideline positioning regarding saffron in depression, with a focus on adult major depressive disorder and related depressive symptomatology. | 4 | Dimech L (2026) | The Role of Saffron in the Treatment of Depression: A Literature Review. |
| Curcumin Depression Meta-Analysis | Across placebo-controlled trials in mild-to-moderate depression, saffron, most commonly administered at 30 mg per day for approximately six weeks, has been associated with clinically meaningful reductions in depressive symptom severity, typically measured using the Hamilton Depression Rating Scale (HAM-D). | 4 | Dimech L (2026) | The Role of Saffron in the Treatment of Depression: A Literature Review. |
| Curcumin Depression Meta-Analysis | Meta-analytic evidence generally indicates superiority over placebo and similar efficacy to selective serotonin reuptake inhibitors (SSRIs), with an overall favourable short-term tolerability profile; however, confidence is constrained by small sample sizes, restricted settings, variable product standardisation (including stigma versus petal preparations), and risk of bias/publication bias. | 4 | Dimech L (2026) | The Role of Saffron in the Treatment of Depression: A Literature Review. |
| Curcumin Depression Meta-Analysis | Saffron ( Crocus sativus L.) has attracted increasing interest as a nutraceutical option for depressive disorders, particularly for patients who experience incomplete response or poor tolerability with conventional treatments. | 4 | Dimech L (2026) | The Role of Saffron in the Treatment of Depression: A Literature Review. |
Source documents