Structured evidence table for Creatine Sleep Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Creatine Sleep Meta-Analysis | This analysis investigated whether the dose or duration of CrM was associated with SEs. | 2 | Gonzalez DE (2026) | Creatine Supplementation Dose and Duration Are Not Associated with Increased Side Effects: A Structured Review and Study-Level Dose-Response Analysis of Randomized Controlled Trials. |
| Creatine Sleep Meta-Analysis | Although dose and duration tertiles were statistically associated with study-level side effect reporting, the effect sizes were uniformly small, events were infrequent, and the reported symptoms were primarily mild and nonspecific. | 2 | Gonzalez DE (2026) | Creatine Supplementation Dose and Duration Are Not Associated with Increased Side Effects: A Structured Review and Study-Level Dose-Response Analysis of Randomized Controlled Trials. |
| Creatine Sleep Meta-Analysis | No consistent exposure-response pattern indicative of clinically meaningful risk was observed. | 2 | Gonzalez DE (2026) | Creatine Supplementation Dose and Duration Are Not Associated with Increased Side Effects: A Structured Review and Study-Level Dose-Response Analysis of Randomized Controlled Trials. |
| Creatine Sleep Meta-Analysis | There are concerns that high-dose and/or long-term creatine monohydrate supplementation (CrM) leads to greater side effects (SEs) compared to placebo. | 2 | Gonzalez DE (2026) | Creatine Supplementation Dose and Duration Are Not Associated with Increased Side Effects: A Structured Review and Study-Level Dose-Response Analysis of Randomized Controlled Trials. |
| Creatine Sleep Meta-Analysis | [] identified improvements in muscular strength, repeated sprint performance, power output, and fatigue resistance due to increased PCr availability, providing strong scientific support for creatine supplementation in athletic populations. | 3 | Kerksick Chad (2026) | The emerging and evolving evidence supporting creatine as an ergogenic aid: history and applications |
| Creatine Sleep Meta-Analysis | There is also some evidence to suggest that short-term CrM supplementation (i.e. | 3 | Kerksick Chad (2026) | The emerging and evolving evidence supporting creatine as an ergogenic aid: history and applications |
| Creatine Sleep Meta-Analysis | [] demonstrated improved repeated cycling performance following five days of CrM (4 × 5 g/day), suggesting a higher sustained power output during repeated cycling sessions. | 3 | Kerksick Chad (2026) | The emerging and evolving evidence supporting creatine as an ergogenic aid: history and applications |
| Creatine Sleep Meta-Analysis | N N 1 2 3 1 Figure 1 2 4 5 2 2 1 6 1,6–11 Creatine (-(aminoiminomethyl)--methyl glycine) is a naturally occurring compound synthesised in the body from glycine, arginine, and methionine and can also be obtained from animal-based proteins or commercially available dietary supplements. | 3 | Kerksick Chad (2026) | The emerging and evolving evidence supporting creatine as an ergogenic aid: history and applications |
Source documents