topicCollagen Sleep Latency Randomized Trial
claimIt is important to gain an understanding of factors associated with poor quality of life as a patient’s perception of quality of life can predict treatment and intervention outcomes [].
evidence level2
citationSingh Prachi (2026)
sourceEffect of an herbal supplement on quality of life in participants with insomnia: A randomized placebo controlled cross-over pilot trial
topicCollagen Sleep Latency Randomized Trial
claimWhile the relationship between insomnia, cardiometabolic risk, and quality of life is recognized, few physicians routinely conduct full sleep histories on their patients, and the patient satisfaction for insomnia treatment remains low [].
evidence level2
citationSingh Prachi (2026)
sourceEffect of an herbal supplement on quality of life in participants with insomnia: A randomized placebo controlled cross-over pilot trial
topicCollagen Sleep Latency Randomized Trial
claimThe intervention duration was based on anecdotal evidence which suggested an acute same day effect on sleep.
evidence level2
citationSingh Prachi (2026)
sourceEffect of an herbal supplement on quality of life in participants with insomnia: A randomized placebo controlled cross-over pilot trial
topicCollagen Sleep Latency Randomized Trial
claim1 2 3 Sleep and quality of life are closely entwined such that sleep disorders like insomnia are closely linked to poor quality of life [].
evidence level2
citationSingh Prachi (2026)
sourceEffect of an herbal supplement on quality of life in participants with insomnia: A randomized placebo controlled cross-over pilot trial
topicCollagen Sleep Latency Randomized Trial
claimBeyond symptoms and impaired quality of life, OSA has been associated with major cardiometabolic and neurocognitive consequences.
evidence level3
citationYuan Sai (2026)
sourceTGF‑β1 in obstructive sleep apnea: linking intermittent hypoxia, upper‑airway remodeling, and systemic comorbidities
topicCollagen Sleep Latency Randomized Trial
claimProspective observational evidence links OSA to increased risks of stroke and mortality [].
evidence level3
citationYuan Sai (2026)
sourceTGF‑β1 in obstructive sleep apnea: linking intermittent hypoxia, upper‑airway remodeling, and systemic comorbidities
topicCollagen Sleep Latency Randomized Trial
claimOSA is also associated with neurocognitive impairment and affective symptoms, and growing literature connects OSA exposures to broader systemic comorbidity phenotypes [–].
evidence level3
citationYuan Sai (2026)
sourceTGF‑β1 in obstructive sleep apnea: linking intermittent hypoxia, upper‑airway remodeling, and systemic comorbidities
topicCollagen Sleep Latency Randomized Trial
claim1 2 3 4 5 8 Obstructive sleep apnea (OSA) is characterized by recurrent episodes of partial or complete upper-airway obstruction during sleep, leading to IH and sleep fragmentation (SF).
evidence level3
citationYuan Sai (2026)
sourceTGF‑β1 in obstructive sleep apnea: linking intermittent hypoxia, upper‑airway remodeling, and systemic comorbidities