Collagen Skin Elasticity Meta-Analysis Evidence Table

Structured evidence table for Collagen Skin Elasticity Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Collagen Skin Elasticity Meta-AnalysisIntroduction Skin aging manifests as wrinkles, reduced elasticity, and roughness due to intrinsic and extrinsic factors.1Nukaly HY (2026)Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
Collagen Skin Elasticity Meta-AnalysisPeptides, particularly oral formulations, significantly improved hydration and brightness, with a modest pooled effect on wrinkle reduction (MD = 0.27, p = 0.04).1Nukaly HY (2026)Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
Collagen Skin Elasticity Meta-AnalysisPeptide-based therapies enhance collagen synthesis and extracellular matrix integrity.1Nukaly HY (2026)Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
Collagen Skin Elasticity Meta-AnalysisThe aim of the present study was to carry out an umbrella review with integrated meta-analyses to capture the breadth of health outcomes associated with collagen supplementation intake.4Ravindran R (2026)Collagen Supplementation for Skin and Musculoskeletal Health: An Umbrella Review of Meta-Analyses on Elasticity, Hydration, and Structural Outcomes.
Collagen Skin Elasticity Meta-AnalysisMeta-regression analyses were conducted to explore potential sources of heterogeneity, and the grading of evidence was carried out using the GRADE.4Ravindran R (2026)Collagen Supplementation for Skin and Musculoskeletal Health: An Umbrella Review of Meta-Analyses on Elasticity, Hydration, and Structural Outcomes.
Collagen Skin Elasticity Meta-AnalysisIn relation to skin, musculoskeletal health, and osteoarthritis conditions, collagen supplementation was consistently associated with favorable outcomes.4Ravindran R (2026)Collagen Supplementation for Skin and Musculoskeletal Health: An Umbrella Review of Meta-Analyses on Elasticity, Hydration, and Structural Outcomes.
Collagen Skin Elasticity Meta-AnalysisCollagen is a protein with multiple roles within the human body, such as supporting fibroblast formation in the dermis, replacing dead skin cells, protecting organs, giving structure, strength and elasticity to the skin, and a primary role in blood clotting.4Ravindran R (2026)Collagen Supplementation for Skin and Musculoskeletal Health: An Umbrella Review of Meta-Analyses on Elasticity, Hydration, and Structural Outcomes.

Source documents

  1. Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials.
  2. Collagen Supplementation for Skin and Musculoskeletal Health: An Umbrella Review of Meta-Analyses on Elasticity, Hydration, and Structural Outcomes.