evidence table
Collagen Nail Growth Meta-Analysis Evidence Table
Structured evidence table for Collagen Nail Growth Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Collagen Nail Growth Meta-Analysis | For TGF-β1, no significant intergroup difference was observed on day 1, whereas a significant difference was found on day 7 ( p = 0.022). | 4 | Göbüt S (2026) | Effect of Adjunctive Ozone Application Protocols on Dentin-Derived Growth Factor Release: An In Vitro Study. |
| Collagen Nail Growth Meta-Analysis | TGF-β1 values increased from day 1 to day 7 in Groups A and C, whereas no significant temporal change was observed in Group B. | 4 | Göbüt S (2026) | Effect of Adjunctive Ozone Application Protocols on Dentin-Derived Growth Factor Release: An In Vitro Study. |
| Collagen Nail Growth Meta-Analysis | However, these in vitro findings indicate measurable growth factor release and should not be interpreted as direct evidence of TGF-β1 activation or clinical regenerative efficacy. | 4 | Göbüt S (2026) | Effect of Adjunctive Ozone Application Protocols on Dentin-Derived Growth Factor Release: An In Vitro Study. |
| Collagen Nail Growth Meta-Analysis | Background/Objectives: Regenerative endodontic treatment (RET) depends on the release of dentin-derived bioactive molecules, which is commonly promoted by ethylenediaminetetraacetic acid (EDTA)-based dentin conditioning. | 4 | Göbüt S (2026) | Effect of Adjunctive Ozone Application Protocols on Dentin-Derived Growth Factor Release: An In Vitro Study. |
| Collagen Nail Growth Meta-Analysis | Skin and its appendages form an integrated system of ectodermal mini-organs that rely on Wnt signaling for lifelong homeostasis and regeneration; yet, the pathway operates in a highly organ-specific manner in each compartment. | 4 | Pulawska-Czub A (2026) | Wnt Signaling Across Adult Skin Mini-Organs: Interfollicular Epidermis, Hair Follicle, and Nail-Implications for Disease and Regeneration. |
| Collagen Nail Growth Meta-Analysis | In interfollicular epidermis, the Wnt activity is spatially graded, thus maintaining the balance between basal progenitor proliferation and terminal differentiation. | 4 | Pulawska-Czub A (2026) | Wnt Signaling Across Adult Skin Mini-Organs: Interfollicular Epidermis, Hair Follicle, and Nail-Implications for Disease and Regeneration. |
Source documents