Structured evidence table for Coenzyme Q10 Statin Myalgia Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Coenzyme Q10 Statin Myalgia Meta-Analysis | They can cause various side effects, in particular statin-associated muscle symptoms (SAMS) associated with mitochondrial dysfunction and micronutrient depletion. | 1 | Kovacic S (2025) | Effects of coenzyme Q10 supplementation on myopathy in statin-treated patients: a systematic review and meta-analysis. |
| Coenzyme Q10 Statin Myalgia Meta-Analysis | Overall, a significant reduction in SAMS, measured as pain intensity, after CoQ10 supplementation was found: weighted mean difference (WMD) -0.96 (95% Confidence Interval -1.88; -0.03), p < 0.05. | 1 | Kovacic S (2025) | Effects of coenzyme Q10 supplementation on myopathy in statin-treated patients: a systematic review and meta-analysis. |
| Coenzyme Q10 Statin Myalgia Meta-Analysis | Statins are effective drugs for lowering hypercholesterolemia and preventing cardiovascular diseases. | 1 | Kovacic S (2025) | Effects of coenzyme Q10 supplementation on myopathy in statin-treated patients: a systematic review and meta-analysis. |
| Coenzyme Q10 Statin Myalgia Meta-Analysis | Despite major advancements in pharmacotherapies and interventional cardiology, substantial residual risk persists among patients with established disease (). | 3 | Wu Xun (2026) | Advances in cardiovascular supplementation: mechanisms, efficacy, and clinical perspectives |
| Coenzyme Q10 Statin Myalgia Meta-Analysis | Additionally, many nutraceuticals are perceived to possess favorable safety and tolerability profiles compared to conventional medications, making them attractive for long-term risk reduction (). | 3 | Wu Xun (2026) | Advances in cardiovascular supplementation: mechanisms, efficacy, and clinical perspectives |
| Coenzyme Q10 Statin Myalgia Meta-Analysis | Banach et al., 2018 Cicero et al., 2017 Sesso et al., 2008 However, the field is marked by heterogeneous and sometimes contradictory evidence. | 3 | Wu Xun (2026) | Advances in cardiovascular supplementation: mechanisms, efficacy, and clinical perspectives |
| Coenzyme Q10 Statin Myalgia Meta-Analysis | Roth et al., 2020 Ganda et al., 2018 Visseren et al., 2021 Cardiovascular disease (CVD) is the leading cause of mortality worldwide, accounting for nearly one-third of global deaths each year (). | 3 | Wu Xun (2026) | Advances in cardiovascular supplementation: mechanisms, efficacy, and clinical perspectives |
Source documents