topicCoenzyme Q10 Endothelial Function Meta-Analysis
claimDespite major advancements in pharmacotherapies and interventional cardiology, substantial residual risk persists among patients with established disease ().
evidence level3
citationWu Xun (2026)
sourceAdvances in cardiovascular supplementation: mechanisms, efficacy, and clinical perspectives
topicCoenzyme Q10 Endothelial Function Meta-Analysis
claimAdditionally, many nutraceuticals are perceived to possess favorable safety and tolerability profiles compared to conventional medications, making them attractive for long-term risk reduction ().
evidence level3
citationWu Xun (2026)
sourceAdvances in cardiovascular supplementation: mechanisms, efficacy, and clinical perspectives
topicCoenzyme Q10 Endothelial Function Meta-Analysis
claimBanach et al., 2018 Cicero et al., 2017 Sesso et al., 2008 However, the field is marked by heterogeneous and sometimes contradictory evidence.
evidence level3
citationWu Xun (2026)
sourceAdvances in cardiovascular supplementation: mechanisms, efficacy, and clinical perspectives
topicCoenzyme Q10 Endothelial Function Meta-Analysis
claimRoth et al., 2020 Ganda et al., 2018 Visseren et al., 2021 Cardiovascular disease (CVD) is the leading cause of mortality worldwide, accounting for nearly one-third of global deaths each year ().
evidence level3
citationWu Xun (2026)
sourceAdvances in cardiovascular supplementation: mechanisms, efficacy, and clinical perspectives
topicCoenzyme Q10 Endothelial Function Meta-Analysis
claim1 2 3 5 6 7 8 9 More than two billion people are at risk of micronutrient deficiencies, which often involve multiple, rather than single, nutrients [,].
evidence level4
citationMuacevic Alexander (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation
topicCoenzyme Q10 Endothelial Function Meta-Analysis
claimThey are widely used to help individuals meet their daily nutrient requirements, support overall health, and address increased nutritional needs associated with pregnancy, aging, and illness.
evidence level4
citationMuacevic Alexander (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation
topicCoenzyme Q10 Endothelial Function Meta-Analysis
claimAccording to the National Health and Nutrition Examination Survey, MVM use in the USA increased from 35% in 1999-2000 [] to 49-52% between 2011 and 2014, with higher usage among women than men [-].
evidence level4
citationMuacevic Alexander (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation
topicCoenzyme Q10 Endothelial Function Meta-Analysis
claimThe most common deficiencies include vitamin A, folic acid, vitamin D, iron, iodine, and zinc, especially among children and women in low- and middle-income countries [-].
evidence level4
citationMuacevic Alexander (2026)
sourceA to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation