Structured evidence table for Cocoa Mood Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Cocoa Mood Meta-Analysis | (2017)highlight challenges associated with the implementation of these treatments, such as access to care and individual variability and adherence. | 1 | Colombage Rebecca L (2026) | Effects of Dietary Flavonoids on Mood and Mental Health: A Systematic Review |
| Cocoa Mood Meta-Analysis | Evidence from observation and intervention studies shows that lifestyle factors such as diet, in particular diets abundant in fruits and vegetables, may play a mediating role in the treatment of mood disorders.Recently, O’Neil et al. | 1 | Colombage Rebecca L (2026) | Effects of Dietary Flavonoids on Mood and Mental Health: A Systematic Review |
| Cocoa Mood Meta-Analysis | (2024),when considering both clinical and cost-effective outcomes, found that lifestyle interventions that target nutrition and physical activity are effective, which suggests suitable treatment alternatives or additions to traditional therapies for mood disorders. | 1 | Colombage Rebecca L (2026) | Effects of Dietary Flavonoids on Mood and Mental Health: A Systematic Review |
| Cocoa Mood Meta-Analysis | Mental health problems have emerged as a pressing and increasingly prevalent concern worldwide, with depression and anxiety standing out as significant contributors to global health-related pressures. | 1 | Colombage Rebecca L (2026) | Effects of Dietary Flavonoids on Mood and Mental Health: A Systematic Review |
| Cocoa Mood Meta-Analysis | Polyphenols strengthen the intestinal barrier and reduce endotoxemia; cocoa bean shell extracts protected against oxysterol‐induced intestinal damage and improved gut microbiota composition in preclinical models (Alia et al. ). | 3 | Akif Adnan (2026) | Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities |
| Cocoa Mood Meta-Analysis | While many epidemiological studies correlate polyphenol‐rich diets (e.g., Mediterranean diet) with reduced NCCD risk, causality is uncertain due to confounding and measurement error. | 3 | Akif Adnan (2026) | Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities |
| Cocoa Mood Meta-Analysis | Controlled trials provide more robust evidence but vary widely in doses, formulations, populations and endpoints. | 3 | Akif Adnan (2026) | Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities |
| Cocoa Mood Meta-Analysis | AMP BBB CNS COMT COSMOS CRP (hs‐CRP) CSF EGCG ENB‐2 (ENB) ENS EVOO FMD GAD‐7 (GAD) GM‐CSF (GM) HDL HOMA‐IR (HOMA) IBS IL IR LDL LPS MCI MMSE NADPH NCCD (NCCDs) PHGG PHQ‐9 (PHQ) PSQI PWV RBANS RCT SCFA SD TNF (TNF‐α) 2024 Non‐communicable chronic diseases account for the majority of morbidity and mortality worldwide. | 3 | Akif Adnan (2026) | Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities |
Source documents