topicBoron Bone Mineral Density Randomized Trial
claim1 2 1 2 Osteoporosis, the primary risk factor for fragility fractures, is highly prevalent and projected to increase as populations age globally [,].
evidence level1
citationTreister-Goltzman Yulia (2026)
sourceEffects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
topicBoron Bone Mineral Density Randomized Trial
claimFragility fractures, particularly of the hip, spine, and wrist, are associated with substantial morbidity, loss of independence, increased mortality, and considerable healthcare costs, making osteoporosis a significant public health concern [,].
evidence level1
citationTreister-Goltzman Yulia (2026)
sourceEffects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
topicBoron Bone Mineral Density Randomized Trial
claimEvidence from multiple in vitro biochemical and cell culture studies [,,], as well as preclinical investigations using ovariectomized and estrogen-deficient rodent models [,,,,,], consistently supports a favorable effect of prunes or prune-derived components on bone metabolism.
evidence level1
citationTreister-Goltzman Yulia (2026)
sourceEffects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials