Structured evidence table for Betaine Sleep Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Betaine Sleep Randomized Trial | Interventions that alter metabolite availability or metabolism, such as caloric restriction (CR) or reduced insulin/IGF‐1 signaling (IIS), extend lifespan across species (Gao et al. ). | 3 | Jiang Yizhou (2026) | Lifespan‐Extending Endogenous Metabolites |
| Betaine Sleep Randomized Trial | This review highlights the role of endogenous metabolites in regulating longevity pathways and evaluates evidence across species to aid understanding metabolic regulation of aging and guiding future investigations. | 3 | Jiang Yizhou (2026) | Lifespan‐Extending Endogenous Metabolites |
| Betaine Sleep Randomized Trial | In UVB‐irradiated hairless mice, oral taurine preserved epidermal moisture and significantly reduced wrinkle formation, suggesting an anti‐photoaging action via its osmolyte and moisturizing roles (Yoshimura et al. ). | 3 | Jiang Yizhou (2026) | Lifespan‐Extending Endogenous Metabolites |
| Betaine Sleep Randomized Trial | 2023 2018 2021 2025 2013 Aging is a multifactorial process driven by the interplay of genetic, environmental, and metabolic perturbations, with dysregulated nutrient sensing and metabolic dysfunction recognized as core hallmarks (Lopez‐Otin et al. ). | 3 | Jiang Yizhou (2026) | Lifespan‐Extending Endogenous Metabolites |
| Betaine Sleep Randomized Trial | 1 2 3 4 5 6 7 8 Considering the crucial role of sleep in human life, sleep disorders, including short sleep duration and poor sleep quality, could increasingly recognized as risk factors for physical [,], and mental dysfunctions []. | 4 | Poursalehi Donya (2026) | Association between methyl donor nutrients intake with sleep duration, sleep quality and biomarkers of oxidative stress and inflammation among adults |
| Betaine Sleep Randomized Trial | According to recent evidence, about one third of adults in developing countries had sleep deficiency []. | 4 | Poursalehi Donya (2026) | Association between methyl donor nutrients intake with sleep duration, sleep quality and biomarkers of oxidative stress and inflammation among adults |
| Betaine Sleep Randomized Trial | A significant relationship was found between age and sleep quality; such that the prevalence of poor sleep quality tended to increase with aging []. | 4 | Poursalehi Donya (2026) | Association between methyl donor nutrients intake with sleep duration, sleep quality and biomarkers of oxidative stress and inflammation among adults |
Source documents