Structured evidence table for B6 Sleep Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| B6 Sleep Meta-Analysis | Concurrently, the number of individuals affected by dementia is anticipated to nearly triple by 2050, with associated treatment costs projected to reach US$2.8 trillion by 2030 []. | 1 | Liu Xing (2026) | Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis |
| B6 Sleep Meta-Analysis | In addition, omega-3 fatty acids support synaptic plasticity and exert anti-inflammatory effects; however, evidence is mixed, as randomized trials in healthy older adults show limited benefits [,], while several analyses report modest improvements in aged or MCI patients [,]. | 1 | Liu Xing (2026) | Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis |
| B6 Sleep Meta-Analysis | Observational studies and recent trials involving antioxidant nutrients, such as pomegranate juice and resveratrol, alongside polyphenols, suggest potential protection for specific cognitive domains (e.g., memory) and reduced dementia risk, although effects are heterogeneous and causality remains unconfirmed [,]. | 1 | Liu Xing (2026) | Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis |
| B6 Sleep Meta-Analysis | 1 2 3 4 5 6 7 8 9 10 The World Health Organization (WHO) projects that by 2050, the global population aged 60 and above will reach 2.1 billion, highlighting the inevitability of global aging []. | 1 | Liu Xing (2026) | Nutritional supplements and cognition in healthy aging and mild cognitive impairment patients: a systematic review and network meta-analysis |
| B6 Sleep Meta-Analysis | Furthermore, several modifiable risk factors such as hypertension, diabetes, obesity, smoking, and sedentary lifestyle play a key role in the development and progression of this disease []. | 3 | Kusyn Natalia (2026) | Well-Known and Novel Behavioural Risk Factors for Heart Failure |
| B6 Sleep Meta-Analysis | This review summarizes the epidemiology of HF and discusses the pathophysiological links between its primary causes and risk factors, highlighting the path of future research required on this topic. | 3 | Kusyn Natalia (2026) | Well-Known and Novel Behavioural Risk Factors for Heart Failure |
| B6 Sleep Meta-Analysis | The search strategy included various key terms such as heart failure, HF risk factors, and lifestyle determinants, in combination with key terms such as tobacco smoking, electronic nicotine delivery systems, e-cigarettes, alcohol consumption, illicit drugs, cocaine, cannabis, caffeine, sleep disorders, psychological stress, obesity, dietary patterns, physical activity and vitamin deficiencies. | 3 | Kusyn Natalia (2026) | Well-Known and Novel Behavioural Risk Factors for Heart Failure |
| B6 Sleep Meta-Analysis | 1 2 3 4 1 3 5 1 1 Figure 1 Heart failure (HF) is a complex clinical syndrome characterized by structural or functional cardiac abnormalities that impair ventricular filling or blood ejection, which leads to inadequate systemic perfusion and elevates intracardiac pressures [,,,]. | 3 | Kusyn Natalia (2026) | Well-Known and Novel Behavioural Risk Factors for Heart Failure |
Source documents