topicAshwagandha Cortisol Meta-Analysis
claimFor example,evaluated nine randomized controlled trials by meta-analysis, and found that the scores of Perceived Stress Questionnaire (PSS), Anxiety Score (HAS) and serum cortisol levels were significantly reduced, indicating that it has a significant anti-pressure effect.
evidence level1
citationZhu XiaoLing (2026)
sourceEffects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis
topicAshwagandha Cortisol Meta-Analysis
claimA study () involving 80 healthy subjects aged 18–45 years showed that, compared with the placebo group, the Ashwagandha-supplemented group significantly improved bench press and leg lift strength, arm circumference and chest circumference, thigh circumference, and maximum oxygen uptake (VOmax) (p < 0.05).
evidence level1
citationZhu XiaoLing (2026)
sourceEffects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis
topicAshwagandha Cortisol Meta-Analysis
claimJa et al., 2016 Supplementary Material To assess the impact of methodological limitations on our findings, we conducted sensitivity analysis excluding studies at high risk of bias.
evidence level1
citationZhu XiaoLing (2026)
sourceEffects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis
topicAshwagandha Cortisol Meta-Analysis
claimWithania somnifera (L.) Dunal Paul et al., 2021 Mikulska et al., 2023 Dar et al., 2015 (Solanaceae), commonly known as Ashwagandha, is a traditional medicinal plant of the Solanaceae family used for thousands of years with a variety of health benefits ().
evidence level1
citationZhu XiaoLing (2026)
sourceEffects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis
topicAshwagandha Cortisol Meta-Analysis
claimBackground: Standardised Ashwagandha root extract (SARE), characterised by its content of bioactive withanolides, is widely used for its antioxidant and adaptogenic properties; however, recent case reports have raised safety concerns, primarily involving non-standardised or multi-ingredient formulations.
evidence level1
citationCoope OC (2026)
sourceBack to the Roots: Safety and Tolerability of Standardised Ashwagandha (<i>Withania somnifera</i>) Root Extract in Healthy Adults-A Systematic Review of Biomarkers and Adverse Events.
topicAshwagandha Cortisol Meta-Analysis
claimThis systematic review evaluated the safety and tolerability of SARE in healthy adults, with a focus on clinical biomarkers and adverse event reporting.
evidence level1
citationCoope OC (2026)
sourceBack to the Roots: Safety and Tolerability of Standardised Ashwagandha (<i>Withania somnifera</i>) Root Extract in Healthy Adults-A Systematic Review of Biomarkers and Adverse Events.