Ashwagandha Cognition Meta-Analysis Evidence Table

Structured evidence table for Ashwagandha Cognition Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Ashwagandha Cognition Meta-AnalysisMethodological quality and risk of bias were assessed with RoB 2, evidence certainty for each outcome was evaluated with GRADE system, and botanical reporting was assessed with the ConPhyMP checklist.1Zhu X (2026)Effects of <i>Withania somnifera (L.) Dunal</i> (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
Ashwagandha Cognition Meta-AnalysisAshwagandha significantly improved memory (SMD = 0.52; 95% CI: 0.27-0.78; P 2 = 29.7%), attention and processing speed (SMD = 0.29; 95% CI: 0.07-0.51; P = 0.009; I 2 = 0%), and executive function (SMD = -0.42; 95% CI: -0.70 to -0.13; P = 0.004; I 2 = 37.5%).1Zhu X (2026)Effects of <i>Withania somnifera (L.) Dunal</i> (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
Ashwagandha Cognition Meta-AnalysisVisuospatial ability improved after excluding one heterogeneous study (SMD = 0.39; 95% CI: 0.08-0.70; P = 0.013; I 2 = 0%).1Zhu X (2026)Effects of <i>Withania somnifera (L.) Dunal</i> (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
Ashwagandha Cognition Meta-AnalysisBackground This study aimed to systematically review and evaluate the effects of Withania somnifera (L.) Dunal (Solanaceae) supplementation on cognitive and physical function in adults by meta-analysis.1Zhu X (2026)Effects of <i>Withania somnifera (L.) Dunal</i> (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
Ashwagandha Cognition Meta-AnalysisMany reviews suggest multiple biological activities, often based on preclinical evidence concerning WS.4Pandey Sudip (2026)Nutraceutical Applications of Withania somnifera : The Scientific Knowledge for Rational Modern Use of the “Ayurvedic Adaptogen”
Ashwagandha Cognition Meta-AnalysisThe objective is to critically evaluate the scientific evidence supporting the claimed effects and to highlight both the strengths and limitations of this plant species, which may be beneficial in various conditions but requires proper understanding for appropriate use.4Pandey Sudip (2026)Nutraceutical Applications of Withania somnifera : The Scientific Knowledge for Rational Modern Use of the “Ayurvedic Adaptogen”
Ashwagandha Cognition Meta-AnalysisOther reported topical applications in India are primarily associated with the management of inflammation and pain across a range of conditions [].4Pandey Sudip (2026)Nutraceutical Applications of Withania somnifera : The Scientific Knowledge for Rational Modern Use of the “Ayurvedic Adaptogen”
Ashwagandha Cognition Meta-AnalysisWithania somnifera 1 2 3 4 5 6 7 8 4 5 4 4 (L.) Dunal has gained significant attention in recent years for its numerous applications in traditional medicine, as well as in food supplements and nutraceuticals, particularly for its energizing effects, enhancement of sports performance, and benefits to central nervous system (CNS) [,,,,,,,].4Pandey Sudip (2026)Nutraceutical Applications of Withania somnifera : The Scientific Knowledge for Rational Modern Use of the “Ayurvedic Adaptogen”
topicAshwagandha Cognition Meta-Analysis
claimMethodological quality and risk of bias were assessed with RoB 2, evidence certainty for each outcome was evaluated with GRADE system, and botanical reporting was assessed with the ConPhyMP checklist.
evidence level1
citationZhu X (2026)
sourceEffects of <i>Withania somnifera (L.) Dunal</i> (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
topicAshwagandha Cognition Meta-Analysis
claimAshwagandha significantly improved memory (SMD = 0.52; 95% CI: 0.27-0.78; P 2 = 29.7%), attention and processing speed (SMD = 0.29; 95% CI: 0.07-0.51; P = 0.009; I 2 = 0%), and executive function (SMD = -0.42; 95% CI: -0.70 to -0.13; P = 0.004; I 2 = 37.5%).
evidence level1
citationZhu X (2026)
sourceEffects of <i>Withania somnifera (L.) Dunal</i> (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
topicAshwagandha Cognition Meta-Analysis
claimVisuospatial ability improved after excluding one heterogeneous study (SMD = 0.39; 95% CI: 0.08-0.70; P = 0.013; I 2 = 0%).
evidence level1
citationZhu X (2026)
sourceEffects of <i>Withania somnifera (L.) Dunal</i> (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
topicAshwagandha Cognition Meta-Analysis
claimBackground This study aimed to systematically review and evaluate the effects of Withania somnifera (L.) Dunal (Solanaceae) supplementation on cognitive and physical function in adults by meta-analysis.
evidence level1
citationZhu X (2026)
sourceEffects of <i>Withania somnifera (L.) Dunal</i> (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
topicAshwagandha Cognition Meta-Analysis
claimMany reviews suggest multiple biological activities, often based on preclinical evidence concerning WS.
evidence level4
citationPandey Sudip (2026)
sourceNutraceutical Applications of Withania somnifera : The Scientific Knowledge for Rational Modern Use of the “Ayurvedic Adaptogen”
topicAshwagandha Cognition Meta-Analysis
claimThe objective is to critically evaluate the scientific evidence supporting the claimed effects and to highlight both the strengths and limitations of this plant species, which may be beneficial in various conditions but requires proper understanding for appropriate use.
evidence level4
citationPandey Sudip (2026)
sourceNutraceutical Applications of Withania somnifera : The Scientific Knowledge for Rational Modern Use of the “Ayurvedic Adaptogen”
topicAshwagandha Cognition Meta-Analysis
claimOther reported topical applications in India are primarily associated with the management of inflammation and pain across a range of conditions [].
evidence level4
citationPandey Sudip (2026)
sourceNutraceutical Applications of Withania somnifera : The Scientific Knowledge for Rational Modern Use of the “Ayurvedic Adaptogen”
topicAshwagandha Cognition Meta-Analysis
claimWithania somnifera 1 2 3 4 5 6 7 8 4 5 4 4 (L.) Dunal has gained significant attention in recent years for its numerous applications in traditional medicine, as well as in food supplements and nutraceuticals, particularly for its energizing effects, enhancement of sports performance, and benefits to central nervous system (CNS) [,,,,,,,].
evidence level4
citationPandey Sudip (2026)
sourceNutraceutical Applications of Withania somnifera : The Scientific Knowledge for Rational Modern Use of the “Ayurvedic Adaptogen”

Source documents

  1. Effects of <i>Withania somnifera (L.) Dunal</i> (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
  2. Nutraceutical Applications of Withania somnifera : The Scientific Knowledge for Rational Modern Use of the “Ayurvedic Adaptogen”